decreased tumor latency_Eef1a1<tm1(FBXW7*)Iaai>/Eef1a1<+>,Tg(Mx1-cre)1Cgn/0

http://metadb.riken.jp/0010308IC57BL6CBAEef1a1tm1FBXW7IaaiEef1a1TgMx1cre1Cgn0Eef1a1tm1FBXW7IaaiTgMx1cre1CgnEef1a1

decreased tumor latency_Eef1a1<tm1(FBXW7*)Iaai>/Eef1a1<+>,Tg(Mx1-cre)1Cgn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• eukaryotic translation elongation factor 1 alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1096881
• transgene insertion 1, University of Cologne
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176072

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Eef1a1<tm1(FBXW7*)Iaai>/Eef1a1<+>,Tg(Mx1-cre)1Cgn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Eef1a1<tm1(FBXW7*)Iaai>|Tg(Mx1-cre)1Cgn|Eef1a1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased tumor latency
  http://purl.obolibrary.org/obo/MP_0010308

文献

http://purl.org/net/cito/citesAsAuthority

• Bryan. King, et.al., The ubiquitin ligase FBXW7 modulates leukemia-initiating cell activity by regulating MYC stability., Cell, 2013, 153
  http://rdf.ncbi.nlm.nih.gov/pubmed/23791182