increased pituitary gland tumor incidence_Kdm5a<tm1.1Kael>/Kdm5a<+>,Rb1<tm1Tyj>/Rb1<+>

http://metadb.riken.jp/0010320I129S2SvPas129S6SvEvTacFVBNKdm5atm11KaelKdm5aRb1tm1TyjRb1Kdm5aRb1tm1TyjKdm5atm11KaelRb1

increased pituitary gland tumor incidence_Kdm5a<tm1.1Kael>/Kdm5a<+>,Rb1<tm1Tyj>/Rb1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• RB transcriptional corepressor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97874
• lysine (K)-specific demethylase 5A
  http://metadb.riken.jp/db/mgi_rdf/MGI:2136980

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kdm5a<tm1.1Kael>/Kdm5a<+>,Rb1<tm1Tyj>/Rb1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kdm5a<+>|Rb1<tm1Tyj>|Kdm5a<tm1.1Kael>|Rb1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S6/SvEvTac * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pituitary gland tumor incidence
  http://purl.obolibrary.org/obo/MP_0010320

文献

http://purl.org/net/cito/citesAsAuthority

• Wenchu. Lin, et.al., Loss of the retinoblastoma binding protein 2 (RBP2) histone demethylase suppresses tumorigenesis in mice lacking Rb1 or Men1., Proceedings of the National Academy of Sciences of the United States of America, 2011, 108
  http://rdf.ncbi.nlm.nih.gov/pubmed/21788502