increased cutaneous melanoma incidence_Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Tyr-cre/ERT2)13Bos/0,Tg(Tyr-NRAS*Q61K)1Bee/0

http://metadb.riken.jp/0010322FVBCgTrp53tm1BrnTgTyrcreERT213BosTgTyrNRASQ61K1BeeTrp53tm1BrnTrp53tm1BrnTgTyrcreERT213Bos0TgTyrNRASQ61K1Bee0TgTyrcreERT213BosTrp53tm1BrnTgTyrNRASQ61K1Bee

increased cutaneous melanoma incidence_Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Tyr-cre/ERT2)13Bos/0,Tg(Tyr-NRAS*Q61K)1Bee/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 13, Marcus Bosenberg
  http://metadb.riken.jp/db/mgi_rdf/MGI:3641202
• transgene insertion 1, Friedrich Beemann
  http://metadb.riken.jp/db/mgi_rdf/MGI:3768643
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Tyr-cre/ERT2)13Bos/0,Tg(Tyr-NRAS*Q61K)1Bee/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tyr-cre/ERT2)13Bos|Trp53<tm1Brn>|Tg(Tyr-NRAS*Q61K)1Bee

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• FVB.Cg-Trp53<tm1Brn> Tg(Tyr-cre/ERT2)13Bos Tg(Tyr-NRAS*Q61K)1Bee

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cutaneous melanoma incidence
  http://purl.obolibrary.org/obo/MP_0010322

文献

http://purl.org/net/cito/citesAsAuthority

• Blake. Ferguson, et.al., Differential roles of the pRb and Arf/p53 pathways in murine naevus and melanoma genesis., Pigment cell & melanoma research, 2010, 23
  http://rdf.ncbi.nlm.nih.gov/pubmed/20718941