increased cutaneous melanoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<+>,Tg(Tyr-NRAS*Q61K)1Bee/?

http://metadb.riken.jp/0010322I129SvC57BL6DBA2SJLCdkn2atm1RdpCdkn2aTgTyrNRASQ61K1BeeTgTyrNRASQ61K1BeeCdkn2aCdkn2atm1Rdp

increased cutaneous melanoma incidence_Cdkn2a<tm1Rdp>/Cdkn2a<+>,Tg(Tyr-NRAS*Q61K)1Bee/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Friedrich Beemann
  http://metadb.riken.jp/db/mgi_rdf/MGI:3768643
• cyclin-dependent kinase inhibitor 2A
  http://metadb.riken.jp/db/mgi_rdf/MGI:104738

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2a<tm1Rdp>/Cdkn2a<+>,Tg(Tyr-NRAS*Q61K)1Bee/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Tyr-NRAS*Q61K)1Bee|Cdkn2a<+>|Cdkn2a<tm1Rdp>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129/Sv * C57BL/6 * DBA/2 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cutaneous melanoma incidence
  http://purl.obolibrary.org/obo/MP_0010322

文献

http://purl.org/net/cito/citesAsAuthority

• Julien. Ackermann, et.al., Metastasizing melanoma formation caused by expression of activated N-RasQ61K on an INK4a-deficient background., Cancer research, 2005, 65
  http://rdf.ncbi.nlm.nih.gov/pubmed/15899789