increased thyroid carcinoma incidence_Tg(tetO-BRAF*V600E)26Jaf/0,Tg(TG-rtTA)30Jaf/0

http://metadb.riken.jp/0010346IFVBNTgtetOBRAFV600E26Jaf0TgTGrtTA30Jaf0TgTGrtTA30JafTgtetOBRAFV600E26Jaf

increased thyroid carcinoma incidence_Tg(tetO-BRAF*V600E)26Jaf/0,Tg(TG-rtTA)30Jaf/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 26, James A Fagin
  http://metadb.riken.jp/db/mgi_rdf/MGI:5524273
• transgene insertion 30, James A Fagin
  http://metadb.riken.jp/db/mgi_rdf/MGI:5524272

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(tetO-BRAF*V600E)26Jaf/0,Tg(TG-rtTA)30Jaf/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(TG-rtTA)30Jaf|Tg(tetO-BRAF*V600E)26Jaf

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased thyroid carcinoma incidence
  http://purl.obolibrary.org/obo/MP_0010346

文献

http://purl.org/net/cito/citesAsAuthority

• Debyani. Chakravarty, et.al., Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation., The Journal of clinical investigation, 2011, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/22105174