Debyani. Chakravarty, et.al., Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation., The Journal of clinical investigation, 2011, 121

http://rdf.ncbi.nlm.nih.gov/pubmed/22105174

Debyani. Chakravarty, et.al., Small-molecule MAPK inhibitors restore radioiodine incorporation in mouse thyroid cancers with conditional BRAF activation., The Journal of clinical investigation, 2011, 121

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-BRAF*V600E)26Jaf
  http://metadb.riken.jp/db/mgi_rdf/MGI:5524276
• Tg(TG-rtTA)30Jaf
  http://metadb.riken.jp/db/mgi_rdf/MGI:5524274

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• increased thyroid tumor incidence_Tg(tetO-BRAF*V600E)26Jaf/0,Tg(TG-rtTA)30Jaf/0
  http://metadb.riken.jp/0010316IFVBNTgtetOBRAFV600E26Jaf0TgTGrtTA30Jaf0TgTGrtTA30JafTgtetOBRAFV600E26Jaf
• increased thyroid carcinoma incidence_Tg(tetO-BRAF*V600E)26Jaf/0,Tg(TG-rtTA)30Jaf/0
  http://metadb.riken.jp/0010346IFVBNTgtetOBRAFV600E26Jaf0TgTGrtTA30Jaf0TgTGrtTA30JafTgtetOBRAFV600E26Jaf
• decreased circulating thyroxine level_Tg(tetO-BRAF*V600E)26Jaf/0,Tg(TG-rtTA)30Jaf/0
  http://metadb.riken.jp/0005478IFVBNTgtetOBRAFV600E26Jaf0TgTGrtTA30Jaf0TgTGrtTA30JafTgtetOBRAFV600E26Jaf
• enlarged thyroid gland_Tg(tetO-BRAF*V600E)26Jaf/0,Tg(TG-rtTA)30Jaf/0
  http://metadb.riken.jp/0005355IFVBNTgtetOBRAFV600E26Jaf0TgTGrtTA30Jaf0TgTGrtTA30JafTgtetOBRAFV600E26Jaf
• decreased circulating thyroid-stimulating hormone level_Tg(tetO-BRAF*V600E)26Jaf/0,Tg(TG-rtTA)30Jaf/0
  http://metadb.riken.jp/0005119IFVBNTgtetOBRAFV600E26Jaf0TgTGrtTA30Jaf0TgTGrtTA30JafTgtetOBRAFV600E26Jaf
• decreased activity of thyroid_Tg(tetO-BRAF*V600E)26Jaf/0,Tg(TG-rtTA)30Jaf/0
  http://metadb.riken.jp/0003503IFVBNTgtetOBRAFV600E26Jaf0TgTGrtTA30Jaf0TgTGrtTA30JafTgtetOBRAFV600E26Jaf

class

http://purl.org/net/cito/citesAsAuthority

• Tg(tetO-BRAF*V600E)26Jaf
  http://metadb.riken.jp/db/mgi_rdf/MGI:5524276
• Tg(TG-rtTA)30Jaf
  http://metadb.riken.jp/db/mgi_rdf/MGI:5524274