increased pituitary melanotroph tumor incidence_Rb1<tm1Tyj>/Rb1<+>,Trp53<tm1Tyj>/Trp53<+>

http://metadb.riken.jp/0010351I129S2SvPasC57BL6Rb1tm1TyjRb1Trp53tm1TyjTrp53Rb1tm1TyjTrp53tm1TyjTrp53Rb1

increased pituitary melanotroph tumor incidence_Rb1<tm1Tyj>/Rb1<+>,Trp53<tm1Tyj>/Trp53<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• RB transcriptional corepressor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97874

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rb1<tm1Tyj>/Rb1<+>,Trp53<tm1Tyj>/Trp53<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rb1<tm1Tyj>|Trp53<tm1Tyj>|Trp53<+>|Rb1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased pituitary melanotroph tumor incidence
  http://purl.obolibrary.org/obo/MP_0010351

文献

http://purl.org/net/cito/citesAsAuthority

• B O. Williams, et.al., Cooperative tumorigenic effects of germline mutations in Rb and p53., Nature genetics, 1994, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/7951317