B O. Williams, et.al., Cooperative tumorigenic effects of germline mutations in Rb and p53., Nature genetics, 1994, 7

http://rdf.ncbi.nlm.nih.gov/pubmed/7951317

B O. Williams, et.al., Cooperative tumorigenic effects of germline mutations in Rb and p53., Nature genetics, 1994, 7

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• premature death_Rb1<tm1Tyj>/Rb1<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002083I129S2SvPasC57BL6Rb1tm1TyjRb1Trp53tm1TyjTrp53Rb1tm1TyjTrp53tm1TyjTrp53Rb1
• increased sarcoma incidence_Rb1<tm1Tyj>/Rb1<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002032I129S2SvPasC57BL6Rb1tm1TyjRb1Trp53tm1TyjTrp53Rb1tm1TyjTrp53tm1TyjTrp53Rb1
• increased pituitary melanotroph tumor incidence_Rb1<tm1Tyj>/Rb1<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0010351I129S2SvPasC57BL6Rb1tm1TyjRb1Trp53tm1TyjTrp53Rb1tm1TyjTrp53tm1TyjTrp53Rb1
• increased thyroid tumor incidence_Rb1<tm1Tyj>/Rb1<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0010316I129S2SvPasC57BL6Rb1tm1TyjRb1Trp53tm1TyjTrp53Rb1tm1TyjTrp53tm1TyjTrp53Rb1
• increased tumor incidence_Rb1<tm1Tyj>/Rb1<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002020I129S2SvPasC57BL6Rb1tm1TyjRb1Trp53tm1TyjTrp53Rb1tm1TyjTrp53tm1TyjTrp53Rb1
• bronchial epithelial hyperplasia_Rb1<tm1Tyj>/Rb1<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0005488I129S2SvPasC57BL6Rb1tm1TyjRb1Trp53tm1TyjTrp53Rb1tm1TyjTrp53tm1TyjTrp53Rb1
• increased pancreatic islet cell carcinoma incidence_Rb1<tm1Tyj>/Rb1<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0010348I129S2SvPasC57BL6Rb1tm1TyjRb1Trp53tm1TyjTrp53Rb1tm1TyjTrp53tm1TyjTrp53Rb1
• abnormal tumor morphology_Rb1<tm1Tyj>/Rb1<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0003448I129S2SvPasC57BL6Rb1tm1TyjRb1Trp53tm1TyjTrp53Rb1tm1TyjTrp53tm1TyjTrp53Rb1
• increased leiomyosarcoma incidence_Rb1<tm1Tyj>/Rb1<+>,Trp53<tm1Tyj>/Trp53<+>
  http://metadb.riken.jp/0002035I129S2SvPasC57BL6Rb1tm1TyjRb1Trp53tm1TyjTrp53Rb1tm1TyjTrp53tm1TyjTrp53Rb1