abnormal dosage compensation, by inactivation of X chromosome_Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>

http://metadb.riken.jp/0010382I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuTsixTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTsixtm11AwuTsixTgCAGEGFP50OsbGtROSA26Sortm1rtTAAwu

abnormal dosage compensation, by inactivation of X chromosome_Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• X (inactive)-specific transcript, opposite strand
  http://metadb.riken.jp/db/mgi_rdf/MGI:1336196
• transgene insertion 50, Research Institute for Microbial Diseases, Osaka University
  http://metadb.riken.jp/db/mgi_rdf/MGI:3760307
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tsix<tm1.1Awu>|Tsix<+>|Tg(CAG-EGFP)50Osb|Gt(ROSA)26Sor<tm1(rtTA)Awu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C3H/HeSlc * C57BL/6J * C57BL/6Slc

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal dosage compensation, by inactivation of X chromosome
  http://purl.obolibrary.org/obo/MP_0010382

文献

http://purl.org/net/cito/citesAsAuthority

• Tatsuya. Ohhata, et.al., Lineage-specific function of the noncoding Tsix RNA for Xist repression and Xi reactivation in mice., Genes & development, 2011, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/21852535