Tatsuya. Ohhata, et.al., Lineage-specific function of the noncoding Tsix RNA for Xist repression and Xi reactivation in mice., Genes & development, 2011, 25

http://rdf.ncbi.nlm.nih.gov/pubmed/21852535

Tatsuya. Ohhata, et.al., Lineage-specific function of the noncoding Tsix RNA for Xist repression and Xi reactivation in mice., Genes & development, 2011, 25

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tsix<tm1.1Awu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5285833

class

http://purl.org/net/cito/citesAsAuthority

• Tsix<tm1.1Awu>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5285833

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic growth retardation_Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>
  http://metadb.riken.jp/0003984I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuTsixTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTsixtm11AwuTsixTgCAGEGFP50OsbGtROSA26Sortm1rtTAAwu
• decreased capillary density_Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>
  http://metadb.riken.jp/0020329I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuTsixTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTsixtm11AwuTsixTgCAGEGFP50OsbGtROSA26Sortm1rtTAAwu
• abnormal DNA methylation_Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>
  http://metadb.riken.jp/0008877I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuTsixTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTsixtm11AwuTsixTgCAGEGFP50OsbGtROSA26Sortm1rtTAAwu
• small placenta_Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>
  http://metadb.riken.jp/0004259I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuTsixTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTsixtm11AwuTsixTgCAGEGFP50OsbGtROSA26Sortm1rtTAAwu
• abnormal imprinting_Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>
  http://metadb.riken.jp/0003787I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuTsixTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTsixtm11AwuTsixTgCAGEGFP50OsbGtROSA26Sortm1rtTAAwu
• abnormal trophoblast layer morphology_Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>
  http://metadb.riken.jp/0005031I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuTsixTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTsixtm11AwuTsixTgCAGEGFP50OsbGtROSA26Sortm1rtTAAwu
• abnormal trophoblast giant cell morphology_Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>
  http://metadb.riken.jp/0005033I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuTsixTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTsixtm11AwuTsixTgCAGEGFP50OsbGtROSA26Sortm1rtTAAwu
• abnormal placenta labyrinth morphology_Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>
  http://metadb.riken.jp/0001716I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuTsixTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTsixtm11AwuTsixTgCAGEGFP50OsbGtROSA26Sortm1rtTAAwu
• embryonic growth retardation_Xist<tm2.1Jae>/Xist<+>
  http://metadb.riken.jp/0003984NSXisttm21JaeXistXistXisttm21Jae
• no abnormal phenotype detected_Tsix<tm1.1Awu>/Tsix<tm1.1Awu>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>
  http://metadb.riken.jp/0002169I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuTsixtm11AwuTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTgCAGEGFP50OsbTsixtm11Awu
• no abnormal phenotype detected_Tsix<tm1.1Awu>/Y,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>
  http://metadb.riken.jp/0002169I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuYTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTsixtm11AwuTgCAGEGFP50OsbGtROSA26Sortm1rtTAAwu
• absent spongiotrophoblast_Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>
  http://metadb.riken.jp/0012100I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuTsixTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTsixtm11AwuTsixTgCAGEGFP50OsbGtROSA26Sortm1rtTAAwu
• increased trophoblast giant cell number_Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>
  http://metadb.riken.jp/0009397I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuTsixTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTsixtm11AwuTsixTgCAGEGFP50OsbGtROSA26Sortm1rtTAAwu
• absent placental labyrinth_Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>
  http://metadb.riken.jp/0003403I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuTsixTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTsixtm11AwuTsixTgCAGEGFP50OsbGtROSA26Sortm1rtTAAwu
• abnormal capillary morphology_Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>
  http://metadb.riken.jp/0003658I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuTsixTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTsixtm11AwuTsixTgCAGEGFP50OsbGtROSA26Sortm1rtTAAwu
• abnormal dosage compensation, by inactivation of X chromosome_Tsix<tm1.1Awu>/Tsix<+>,Tg(CAG-EGFP)50Osb/0,Gt(ROSA)26Sor<tm1(rtTA)Awu>/Gt(ROSA)26Sor<tm1(rtTA)Awu>
  http://metadb.riken.jp/0010382I129P2OlaHsd129S4SvJaeC3HHeSlcC57BL6JC57BL6SlcTsixtm11AwuTsixTgCAGEGFP50Osb0GtROSA26Sortm1rtTAAwuGtROSA26Sortm1rtTAAwuTsixtm11AwuTsixTgCAGEGFP50OsbGtROSA26Sortm1rtTAAwu