ventricular septal defect_Adam12<tm1Asf>/Adam12<tm1Asf>,Adam15<tm1Bbl>/Adam15<tm1Bbl>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>

http://metadb.riken.jp/0010402I129P2OlaHsd129S1Sv129X1SvJC57BL6Adam12tm1AsfAdam12tm1AsfAdam15tm1BblAdam15tm1BblAdam19GtBetageo1BblAdam19GtBetageo1BblAdam9tm1BblAdam9tm1BblAdam15tm1BblAdam9tm1BblAdam19GtBetageo1BblAdam12tm1Asf

ventricular septal defect_Adam12<tm1Asf>/Adam12<tm1Asf>,Adam15<tm1Bbl>/Adam15<tm1Bbl>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• a disintegrin and metallopeptidase domain 12 (meltrin alpha)
  http://metadb.riken.jp/db/mgi_rdf/MGI:105378
• a disintegrin and metallopeptidase domain 19 (meltrin beta)
  http://metadb.riken.jp/db/mgi_rdf/MGI:105377
• a disintegrin and metallopeptidase domain 15 (metargidin)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1333882
• a disintegrin and metallopeptidase domain 9 (meltrin gamma)
  http://metadb.riken.jp/db/mgi_rdf/MGI:105376

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Adam12<tm1Asf>/Adam12<tm1Asf>,Adam15<tm1Bbl>/Adam15<tm1Bbl>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Adam15<tm1Bbl>|Adam9<tm1Bbl>|Adam19<Gt(Betageo)1Bbl>|Adam12<tm1Asf>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• ventricular septal defect
  http://purl.obolibrary.org/obo/MP_0010402

文献

http://purl.org/net/cito/citesAsAuthority

• Keisuke. Horiuchi, et.al., Evaluation of the contributions of ADAMs 9, 12, 15, 17, and 19 to heart development and ectodomain shedding of neuregulins beta1 and beta2., Developmental biology, 2005, 283
  http://rdf.ncbi.nlm.nih.gov/pubmed/15936750