Keisuke. Horiuchi, et.al., Evaluation of the contributions of ADAMs 9, 12, 15, 17, and 19 to heart development and ectodomain shedding of neuregulins beta1 and beta2., Developmental biology, 2005, 283

http://rdf.ncbi.nlm.nih.gov/pubmed/15936750

Keisuke. Horiuchi, et.al., Evaluation of the contributions of ADAMs 9, 12, 15, 17, and 19 to heart development and ectodomain shedding of neuregulins beta1 and beta2., Developmental biology, 2005, 283

pubmed

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal tricuspid valve morphology_Adam15<tm1Bbl>/Adam15<tm1Bbl>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>
  http://metadb.riken.jp/0002624I129Sv129P2OlaHsd129X1SvJC57BL6Adam15tm1BblAdam15tm1BblAdam19GtBetageo1BblAdam19GtBetageo1BblAdam15tm1BblAdam19GtBetageo1Bbl
• thick tricuspid valve_Adam15<tm1Bbl>/Adam15<tm1Bbl>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>
  http://metadb.riken.jp/0010629I129Sv129P2OlaHsd129X1SvJC57BL6Adam15tm1BblAdam15tm1BblAdam19GtBetageo1BblAdam19GtBetageo1BblAdam15tm1BblAdam19GtBetageo1Bbl
• abnormal semilunar valve morphology_Adam12<tm1Asf>/Adam12<tm1Asf>,Adam15<tm1Bbl>/Adam15<tm1Bbl>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>
  http://metadb.riken.jp/0002746I129P2OlaHsd129S1Sv129X1SvJC57BL6Adam12tm1AsfAdam12tm1AsfAdam15tm1BblAdam15tm1BblAdam19GtBetageo1BblAdam19GtBetageo1BblAdam9tm1BblAdam9tm1BblAdam15tm1BblAdam9tm1BblAdam19GtBetageo1BblAdam12tm1Asf
• thick aortic valve_Adam17<tm1Imx>/Adam17<tm1Imx>
  http://metadb.riken.jp/0010594I129C57BL6Adam17tm1ImxAdam17tm1ImxAdam17tm1Imx
• abnormal mitral valve morphology_Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>
  http://metadb.riken.jp/0000286I129Sv129P2OlaHsdC57BL6Adam19GtBetageo1BblAdam19GtBetageo1BblAdam9tm1BblAdam9tm1BblAdam9tm1BblAdam19GtBetageo1Bbl
• enlarged mitral valve_Adam12<tm1Asf>/Adam12<tm1Asf>,Adam15<tm1Bbl>/Adam15<tm1Bbl>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>
  http://metadb.riken.jp/0010618I129P2OlaHsd129S1Sv129X1SvJC57BL6Adam12tm1AsfAdam12tm1AsfAdam15tm1BblAdam15tm1BblAdam19GtBetageo1BblAdam19GtBetageo1BblAdam9tm1BblAdam9tm1BblAdam15tm1BblAdam9tm1BblAdam19GtBetageo1BblAdam12tm1Asf
• enlarged mitral valve_Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>
  http://metadb.riken.jp/0010618I129Sv129P2OlaHsdC57BL6Adam19GtBetageo1BblAdam19GtBetageo1BblAdam9tm1BblAdam9tm1BblAdam9tm1BblAdam19GtBetageo1Bbl
• ventricular septal defect_Adam17<tm1Imx>/Adam17<tm1Imx>
  http://metadb.riken.jp/0010402I129C57BL6Adam17tm1ImxAdam17tm1ImxAdam17tm1Imx
• absent myocardial trabeculae_Adam17<tm1Imx>/Adam17<tm1Imx>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>
  http://metadb.riken.jp/0000293I129Sv129P2OlaHsdC57BL6Adam17tm1ImxAdam17tm1ImxAdam19GtBetageo1BblAdam19GtBetageo1BblAdam17tm1ImxAdam19GtBetageo1Bbl
• thick mitral valve_Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>
  http://metadb.riken.jp/0010620I129Sv129P2OlaHsdC57BL6Adam19GtBetageo1BblAdam19GtBetageo1BblAdam9tm1BblAdam9tm1BblAdam9tm1BblAdam19GtBetageo1Bbl
• thin ventricular wall_Adam17<tm1Imx>/Adam17<tm1Imx>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>
  http://metadb.riken.jp/0000280I129Sv129P2OlaHsdC57BL6Adam17tm1ImxAdam17tm1ImxAdam19GtBetageo1BblAdam19GtBetageo1BblAdam17tm1ImxAdam19GtBetageo1Bbl
• enlarged tricuspid valve_Adam12<tm1Asf>/Adam12<tm1Asf>,Adam15<tm1Bbl>/Adam15<tm1Bbl>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>
  http://metadb.riken.jp/0010627I129P2OlaHsd129S1Sv129X1SvJC57BL6Adam12tm1AsfAdam12tm1AsfAdam15tm1BblAdam15tm1BblAdam19GtBetageo1BblAdam19GtBetageo1BblAdam9tm1BblAdam9tm1BblAdam15tm1BblAdam9tm1BblAdam19GtBetageo1BblAdam12tm1Asf
• ventricular septal defect_Adam12<tm1Asf>/Adam12<tm1Asf>,Adam15<tm1Bbl>/Adam15<tm1Bbl>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>
  http://metadb.riken.jp/0010402I129P2OlaHsd129S1Sv129X1SvJC57BL6Adam12tm1AsfAdam12tm1AsfAdam15tm1BblAdam15tm1BblAdam19GtBetageo1BblAdam19GtBetageo1BblAdam9tm1BblAdam9tm1BblAdam15tm1BblAdam9tm1BblAdam19GtBetageo1BblAdam12tm1Asf
• thick tricuspid valve_Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>
  http://metadb.riken.jp/0010629I129Sv129P2OlaHsdC57BL6Adam19GtBetageo1BblAdam19GtBetageo1BblAdam9tm1BblAdam9tm1BblAdam9tm1BblAdam19GtBetageo1Bbl
• double outlet right ventricle_Adam12<tm1Asf>/Adam12<tm1Asf>,Adam15<tm1Bbl>/Adam15<tm1Bbl>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>
  http://metadb.riken.jp/0000284I129P2OlaHsd129S1Sv129X1SvJC57BL6Adam12tm1AsfAdam12tm1AsfAdam15tm1BblAdam15tm1BblAdam19GtBetageo1BblAdam19GtBetageo1BblAdam9tm1BblAdam9tm1BblAdam15tm1BblAdam9tm1BblAdam19GtBetageo1BblAdam12tm1Asf
• perimembraneous ventricular septal defect_Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>
  http://metadb.riken.jp/0010418I129Sv129P2OlaHsdC57BL6Adam19GtBetageo1BblAdam19GtBetageo1BblAdam19GtBetageo1Bbl
• perinatal lethality, incomplete penetrance_Adam12<tm1Asf>/Adam12<tm1Asf>,Adam15<tm1Bbl>/Adam15<tm1Bbl>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>
  http://metadb.riken.jp/0011090I129P2OlaHsd129S1Sv129X1SvJC57BL6Adam12tm1AsfAdam12tm1AsfAdam15tm1BblAdam15tm1BblAdam19GtBetageo1BblAdam19GtBetageo1BblAdam9tm1BblAdam9tm1BblAdam15tm1BblAdam9tm1BblAdam19GtBetageo1BblAdam12tm1Asf
• lethality throughout fetal growth and development, complete penetrance_Adam17<tm1Imx>/Adam17<tm1Imx>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>
  http://metadb.riken.jp/0011099I129Sv129P2OlaHsdC57BL6Adam17tm1ImxAdam17tm1ImxAdam19GtBetageo1BblAdam19GtBetageo1BblAdam17tm1ImxAdam19GtBetageo1Bbl
• abnormal tricuspid valve morphology_Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>
  http://metadb.riken.jp/0002624I129Sv129P2OlaHsdC57BL6Adam19GtBetageo1BblAdam19GtBetageo1BblAdam19GtBetageo1Bbl
• abnormal myocardium layer morphology_Adam17<tm1Imx>/Adam17<tm1Imx>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>
  http://metadb.riken.jp/0005329I129Sv129P2OlaHsdC57BL6Adam17tm1ImxAdam17tm1ImxAdam19GtBetageo1BblAdam19GtBetageo1BblAdam17tm1ImxAdam19GtBetageo1Bbl
• abnormal tricuspid valve morphology_Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>
  http://metadb.riken.jp/0002624I129Sv129P2OlaHsdC57BL6Adam19GtBetageo1BblAdam19GtBetageo1BblAdam9tm1BblAdam9tm1BblAdam9tm1BblAdam19GtBetageo1Bbl
• thick aortic valve_Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>
  http://metadb.riken.jp/0010594I129Sv129P2OlaHsdC57BL6Adam19GtBetageo1BblAdam19GtBetageo1BblAdam19GtBetageo1Bbl
• double outlet right ventricle_Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>
  http://metadb.riken.jp/0000284I129Sv129P2OlaHsdC57BL6Adam19GtBetageo1BblAdam19GtBetageo1BblAdam9tm1BblAdam9tm1BblAdam9tm1BblAdam19GtBetageo1Bbl
• abnormal heart valve morphology_Adam12<tm1Asf>/Adam12<tm1Asf>,Adam15<tm1Bbl>/Adam15<tm1Bbl>,Adam19<Gt(Betageo)1Bbl>/Adam19<Gt(Betageo)1Bbl>,Adam9<tm1Bbl>/Adam9<tm1Bbl>
  http://metadb.riken.jp/0000285I129P2OlaHsd129S1Sv129X1SvJC57BL6Adam12tm1AsfAdam12tm1AsfAdam15tm1BblAdam15tm1BblAdam19GtBetageo1BblAdam19GtBetageo1BblAdam9tm1BblAdam9tm1BblAdam15tm1BblAdam9tm1BblAdam19GtBetageo1BblAdam12tm1Asf