ventricular septal defect_Mapk1<tm1Melo>/Mapk1<+>,Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/0,Tg(Tek-cre)12Flv/0

http://metadb.riken.jp/0010402I129S2SvPasC3HC57BL6FVBNMapk1tm1MeloMapk1TgCAGcatPtpn11Q97R1Rbns0TgTekcre12Flv0TgCAGcatPtpn11Q97R1RbnsTgTekcre12FlvMapk1tm1MeloMapk1

ventricular septal defect_Mapk1<tm1Melo>/Mapk1<+>,Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/0,Tg(Tek-cre)12Flv/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Jeffrey Robbins
  http://metadb.riken.jp/db/mgi_rdf/MGI:3822047
• transgene insertion 12, Richard A Flavell
  http://metadb.riken.jp/db/mgi_rdf/MGI:2136409
• mitogen-activated protein kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1346858

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mapk1<tm1Melo>/Mapk1<+>,Tg(CAG-cat,-Ptpn11*Q97R)1Rbns/0,Tg(Tek-cre)12Flv/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CAG-cat,-Ptpn11*Q97R)1Rbns|Tg(Tek-cre)12Flv|Mapk1<tm1Melo>|Mapk1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C3H * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• ventricular septal defect
  http://purl.obolibrary.org/obo/MP_0010402

文献

http://purl.org/net/cito/citesAsAuthority

• Maike. Krenz, et.al., Role of ERK1/2 signaling in congenital valve malformations in Noonan syndrome., Proceedings of the National Academy of Sciences of the United States of America, 2008, 105
  http://rdf.ncbi.nlm.nih.gov/pubmed/19017799