atrioventricular septal defect_Isl1<tm1(cre)Sev>/Isl1<+>,Tg(CAG-lacZ,-BMPR1A*,-EGFP)1Mis/0

http://metadb.riken.jp/0010412I129S7SvEvBrdIsl1tm1creSevIsl1TgCAGlacZBMPR1AEGFP1Mis0Isl1TgCAGlacZBMPR1AEGFP1MisIsl1tm1creSev

atrioventricular septal defect_Isl1<tm1(cre)Sev>/Isl1<+>,Tg(CAG-lacZ,-BMPR1A*,-EGFP)1Mis/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Yuji Mishina
  http://metadb.riken.jp/db/mgi_rdf/MGI:3829214
• ISL1 transcription factor, LIM/homeodomain
  http://metadb.riken.jp/db/mgi_rdf/MGI:101791

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Isl1<tm1(cre)Sev>/Isl1<+>,Tg(CAG-lacZ,-BMPR1A*,-EGFP)1Mis/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Isl1<+>|Tg(CAG-lacZ,-BMPR1A*,-EGFP)1Mis|Isl1<tm1(cre)Sev>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• atrioventricular septal defect
  http://purl.obolibrary.org/obo/MP_0010412

文献

http://purl.org/net/cito/citesAsAuthority

• Nathalie. Gaborit, et.al., Cooperative and antagonistic roles for Irx3 and Irx5 in cardiac morphogenesis and postnatal physiology., Development (Cambridge, England), 2012, 139
  http://rdf.ncbi.nlm.nih.gov/pubmed/22992950