Nathalie. Gaborit, et.al., Cooperative and antagonistic roles for Irx3 and Irx5 in cardiac morphogenesis and postnatal physiology., Development (Cambridge, England), 2012, 139

http://rdf.ncbi.nlm.nih.gov/pubmed/22992950

Nathalie. Gaborit, et.al., Cooperative and antagonistic roles for Irx3 and Irx5 in cardiac morphogenesis and postnatal physiology., Development (Cambridge, England), 2012, 139

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Irx3<tm3Hui>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5444472
• Irx3<tm3.1Hui>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5444473
• Irx5<tm3Hui>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5444483

class

http://purl.org/net/cito/citesAsAuthority

• Irx3<tm3Hui>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5444472
• Irx3<tm3.1Hui>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5444473
• Irx5<tm3Hui>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5444483

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• atrioventricular septal defect_Tg(CAG-lacZ,-BMPR1A*,-EGFP)1Mis/0,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0010412I129S7SvEvBrdC57BL6SJLTgCAGlacZBMPR1AEGFP1Mis0TgTekcre1Ywa0TgTekcre1YwaTgCAGlacZBMPR1AEGFP1Mis
• abnormal cardiac outflow tract development_Irx3<tm3Hui>/Irx3<tm3Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0006126I129SSvIrx3tm3HuiIrx3tm3HuiIrx5tm3HuiIrx5tm3HuiIsl1tm1creSevIsl1Irx3tm3HuiIsl1Irx5tm3HuiIsl1tm1creSev
• abnormal interatrial septum morphology_Irx3<tm3Hui>/Irx3<tm3Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0000282I129SSvIrx3tm3HuiIrx3tm3HuiIrx5tm3HuiIrx5tm3HuiIsl1tm1creSevIsl1Irx3tm3HuiIsl1Irx5tm3HuiIsl1tm1creSev
• double outlet right ventricle_Irx3<tm3Hui>/Irx3<tm3Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0000284IC57BL6SJLIrx3tm3HuiIrx3tm3HuiIrx5tm3HuiIrx5tm3HuiTgTekcre1Ywa0TgTekcre1YwaIrx5tm3HuiIrx3tm3Hui
• atrioventricular septal defect_Irx3<tm3.1Hui>/Irx3<tm3.1Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>
  http://metadb.riken.jp/0010412NSIrx3tm31HuiIrx3tm31HuiIrx5tm3HuiIrx5tm3HuiIrx5tm3HuiIrx3tm31Hui
• atrioventricular septal defect_Irx3<tm3Hui>/Irx3<tm3Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0010412IC57BL6SJLIrx3tm3HuiIrx3tm3HuiIrx5tm3HuiIrx5tm3HuiTgTekcre1Ywa0TgTekcre1YwaIrx5tm3HuiIrx3tm3Hui
• atrial septal defect_Irx3<tm3Hui>/Irx3<tm3Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0010403IC57BL6SJLIrx3tm3HuiIrx3tm3HuiIrx5tm3HuiIrx5tm3HuiTgTekcre1Ywa0TgTekcre1YwaIrx5tm3HuiIrx3tm3Hui
• abnormal heart septum morphology_Irx3<tm3.1Hui>/Irx3<tm3.1Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>
  http://metadb.riken.jp/0006113NSIrx3tm31HuiIrx3tm31HuiIrx5tm3HuiIrx5tm3HuiIrx5tm3HuiIrx3tm31Hui
• double outlet right ventricle_Irx3<tm3Hui>/Irx3<tm3Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>,Tg(Mef2c-cre)#Blk/0
  http://metadb.riken.jp/0000284NSIrx3tm3HuiIrx3tm3HuiIrx5tm3HuiIrx5tm3HuiTgMef2ccreBlk0Irx5tm3HuiTgMef2ccreBlkIrx3tm3Hui
• lethality throughout fetal growth and development, complete penetrance_Irx3<tm3.1Hui>/Irx3<tm3.1Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>
  http://metadb.riken.jp/0011099NSIrx3tm31HuiIrx3tm31HuiIrx5tm3HuiIrx5tm3HuiIrx5tm3HuiIrx3tm31Hui
• abnormal cardiac outflow tract development_Irx3<tm3Hui>/Irx3<tm3Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>,Tg(Tek-cre)1Ywa/0
  http://metadb.riken.jp/0006126IC57BL6SJLIrx3tm3HuiIrx3tm3HuiIrx5tm3HuiIrx5tm3HuiTgTekcre1Ywa0TgTekcre1YwaIrx5tm3HuiIrx3tm3Hui
• abnormal cardiac outflow tract development_Irx3<tm3Hui>/Irx3<tm3Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>,Tg(Mef2c-cre)#Blk/0
  http://metadb.riken.jp/0006126NSIrx3tm3HuiIrx3tm3HuiIrx5tm3HuiIrx5tm3HuiTgMef2ccreBlk0Irx5tm3HuiTgMef2ccreBlkIrx3tm3Hui
• prolonged PR interval_Irx3<tm3Hui>/Irx3<tm3Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0003896IFVBIrx3tm3HuiIrx3tm3HuiIrx5tm3HuiIrx5tm3HuiA1cfTgMyh6creEsr11Jmk0Irx3tm3HuiA1cfTgMyh6creEsr11JmkIrx5tm3Hui
• atrioventricular septal defect_Irx3<tm3Hui>/Irx3<tm3Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0010412I129SSvIrx3tm3HuiIrx3tm3HuiIrx5tm3HuiIrx5tm3HuiIsl1tm1creSevIsl1Irx3tm3HuiIsl1Irx5tm3HuiIsl1tm1creSev
• double outlet right ventricle_Irx3<tm3.1Hui>/Irx3<tm3.1Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>
  http://metadb.riken.jp/0000284NSIrx3tm31HuiIrx3tm31HuiIrx5tm3HuiIrx5tm3HuiIrx5tm3HuiIrx3tm31Hui
• abnormal cardiac outflow tract development_Irx3<tm3.1Hui>/Irx3<tm3.1Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>
  http://metadb.riken.jp/0006126NSIrx3tm31HuiIrx3tm31HuiIrx5tm3HuiIrx5tm3HuiIrx5tm3HuiIrx3tm31Hui
• atrial septal defect_Irx3<tm3.1Hui>/Irx3<tm3.1Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>
  http://metadb.riken.jp/0010403NSIrx3tm31HuiIrx3tm31HuiIrx5tm3HuiIrx5tm3HuiIrx5tm3HuiIrx3tm31Hui
• double outlet right ventricle_Irx3<tm3Hui>/Irx3<tm3Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0000284I129SSvIrx3tm3HuiIrx3tm3HuiIrx5tm3HuiIrx5tm3HuiIsl1tm1creSevIsl1Irx3tm3HuiIsl1Irx5tm3HuiIsl1tm1creSev
• atrial septal defect_Irx3<tm3Hui>/Irx3<tm3Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0010403I129SSvIrx3tm3HuiIrx3tm3HuiIrx5tm3HuiIrx5tm3HuiIsl1tm1creSevIsl1Irx3tm3HuiIsl1Irx5tm3HuiIsl1tm1creSev
• abnormal heart development_Irx3<tm3.1Hui>/Irx3<tm3.1Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>
  http://metadb.riken.jp/0000267NSIrx3tm31HuiIrx3tm31HuiIrx5tm3HuiIrx5tm3HuiIrx5tm3HuiIrx3tm31Hui
• atrioventricular septal defect_Isl1<tm1(cre)Sev>/Isl1<+>,Tg(CAG-lacZ,-BMPR1A*,-EGFP)1Mis/0
  http://metadb.riken.jp/0010412I129S7SvEvBrdIsl1tm1creSevIsl1TgCAGlacZBMPR1AEGFP1Mis0Isl1TgCAGlacZBMPR1AEGFP1MisIsl1tm1creSev
• persistent truncus arteriosis_Irx3<tm3Hui>/Irx3<tm3Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>,Isl1<tm1(cre)Sev>/Isl1<+>
  http://metadb.riken.jp/0002633I129SSvIrx3tm3HuiIrx3tm3HuiIrx5tm3HuiIrx5tm3HuiIsl1tm1creSevIsl1Irx3tm3HuiIsl1Irx5tm3HuiIsl1tm1creSev
• abnormal interatrial septum morphology_Irx3<tm3.1Hui>/Irx3<tm3.1Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>
  http://metadb.riken.jp/0000282NSIrx3tm31HuiIrx3tm31HuiIrx5tm3HuiIrx5tm3HuiIrx5tm3HuiIrx3tm31Hui
• prolonged QRS complex duration_Irx3<tm3Hui>/Irx3<tm3Hui>,Irx5<tm3Hui>/Irx5<tm3Hui>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0
  http://metadb.riken.jp/0010392IFVBIrx3tm3HuiIrx3tm3HuiIrx5tm3HuiIrx5tm3HuiA1cfTgMyh6creEsr11Jmk0Irx3tm3HuiA1cfTgMyh6creEsr11JmkIrx5tm3Hui