perimembraneous ventricular septal defect_Hand1<tm1Eno>/Hand1<tm2Eno>,Tg(Myh6-cre)2182Mds/0

http://metadb.riken.jp/0010418EI129S6SvEvTacBlackSwissorI129S6SvEvTacC57BL6Hand1tm1EnoHand1tm2EnoTgMyh6cre2182Mds0Hand1tm1EnoTgMyh6cre2182MdsHand1tm2Eno

perimembraneous ventricular septal defect_Hand1<tm1Eno>/Hand1<tm2Eno>,Tg(Myh6-cre)2182Mds/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2182, Michael D Schneider
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447636
• heart and neural crest derivatives expressed 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:103577

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hand1<tm1Eno>/Hand1<tm2Eno>,Tg(Myh6-cre)2182Mds/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hand1<tm1Eno>|Tg(Myh6-cre)2182Mds|Hand1<tm2Eno>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129S6/SvEvTac * Black Swiss) or (involves: 129S6/SvEvTac * C57BL/6)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• perimembraneous ventricular septal defect
  http://purl.obolibrary.org/obo/MP_0010418

文献

http://purl.org/net/cito/citesAsAuthority

• David G. McFadden, et.al., The Hand1 and Hand2 transcription factors regulate expansion of the embryonic cardiac ventricles in a gene dosage-dependent manner., Development (Cambridge, England), 2005, 132
  http://rdf.ncbi.nlm.nih.gov/pubmed/15576406