tumor regression_Trp53<tm1Glo>/Trp53<tm4Glo>,Tg(CAG-cre/Esr1*)5Amc/0

http://metadb.riken.jp/0010537I129S7SvEvBrdC57BL6CBATrp53tm1GloTrp53tm4GloTgCAGcreEsr15Amc0TgCAGcreEsr15AmcTrp53tm1GloTrp53tm4Glo

tumor regression_Trp53<tm1Glo>/Trp53<tm4Glo>,Tg(CAG-cre/Esr1*)5Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 5, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182765

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Glo>/Trp53<tm4Glo>,Tg(CAG-cre/Esr1*)5Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(CAG-cre/Esr1*)5Amc|Trp53<tm1Glo>|Trp53<tm4Glo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• tumor regression
  http://purl.obolibrary.org/obo/MP_0010537

文献

http://purl.org/net/cito/citesAsAuthority

• Yongxing. Wang, et.al., Restoring expression of wild-type p53 suppresses tumor growth but does not cause tumor regression in mice with a p53 missense mutation., The Journal of clinical investigation, 2011, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/21285512