heart block_Tg(Myh6-tTA)6Smbf/0,Tg(tetO-NOS2,-lacZ)240iMhus/0

http://metadb.riken.jp/0010559IC57BL6CBATgMyh6tTA6Smbf0TgtetONOS2lacZ240iMhus0TgtetONOS2lacZ240iMhusTgMyh6tTA6Smbf

heart block_Tg(Myh6-tTA)6Smbf/0,Tg(tetO-NOS2,-lacZ)240iMhus/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 240i, Mansoor Husain
  http://metadb.riken.jp/db/mgi_rdf/MGI:4837724
• transgene insertion 6, Section of Myocardial Biology - Fishman Lab
  http://metadb.riken.jp/db/mgi_rdf/MGI:2665552

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Myh6-tTA)6Smbf/0,Tg(tetO-NOS2,-lacZ)240iMhus/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-NOS2,-lacZ)240iMhus|Tg(Myh6-tTA)6Smbf

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• heart block
  http://purl.obolibrary.org/obo/MP_0010559

文献

http://purl.org/net/cito/citesAsAuthority

• Imran N. Mungrue, et.al., Cardiomyocyte overexpression of iNOS in mice results in peroxynitrite generation, heart block, and sudden death., The Journal of clinical investigation, 2002, 109
  http://rdf.ncbi.nlm.nih.gov/pubmed/11901182