decreased trabecular bone mass_Cdk7<Gt(D032B11)1.1Wrst>/Cdk7<Gt(D032B11)1.1Wrst>,Tg(UBC-cre/ERT2)1Ejb/0

http://metadb.riken.jp/0010873I129SSvPas129S2SvPasC57BL6SJLCdk7GtD032B1111WrstCdk7GtD032B1111WrstTgUBCcreERT21Ejb0Cdk7GtD032B1111WrstTgUBCcreERT21Ejb

decreased trabecular bone mass_Cdk7<Gt(D032B11)1.1Wrst>/Cdk7<Gt(D032B11)1.1Wrst>,Tg(UBC-cre/ERT2)1Ejb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Eric J Brown
  http://metadb.riken.jp/db/mgi_rdf/MGI:3707330
• cyclin-dependent kinase 7
  http://metadb.riken.jp/db/mgi_rdf/MGI:102956

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdk7<Gt(D032B11)1.1Wrst>/Cdk7<Gt(D032B11)1.1Wrst>,Tg(UBC-cre/ERT2)1Ejb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdk7<Gt(D032B11)1.1Wrst>|Tg(UBC-cre/ERT2)1Ejb

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvPas * 129S2/SvPas * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased trabecular bone mass
  http://purl.obolibrary.org/obo/MP_0010873

文献

http://purl.org/net/cito/citesAsAuthority

• Miguel. Ganuza, et.al., Genetic inactivation of Cdk7 leads to cell cycle arrest and induces premature aging due to adult stem cell exhaustion., The EMBO journal, 2012, 31
  http://rdf.ncbi.nlm.nih.gov/pubmed/22505032