decreased trabecular bone volume_Tg(Col1a1-Dkk1)1Hmk/?

http://metadb.riken.jp/0010879B6FVBTgCol1a1Dkk11HmkTgCol1a1Dkk11HmkTgCol1a1Dkk11Hmk

decreased trabecular bone volume_Tg(Col1a1-Dkk1)1Hmk/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Henry M Kronenberg
  http://metadb.riken.jp/db/mgi_rdf/MGI:5818209

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Tg(Col1a1-Dkk1)1Hmk/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Col1a1-Dkk1)1Hmk

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.FVB-Tg(Col1a1-Dkk1)1Hmk

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased trabecular bone volume
  http://purl.obolibrary.org/obo/MP_0010879

文献

http://purl.org/net/cito/citesAsAuthority

• Jun. Guo, et.al., Suppression of Wnt signaling by Dkk1 attenuates PTH-mediated stromal cell response and new bone formation., Cell metabolism, 2010, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/20142103
• Heather E. Fleming, et.al., Wnt signaling in the niche enforces hematopoietic stem cell quiescence and is necessary to preserve self-renewal in vivo., Cell stem cell, 2008, 2
  http://rdf.ncbi.nlm.nih.gov/pubmed/18371452