Jun. Guo, et.al., Suppression of Wnt signaling by Dkk1 attenuates PTH-mediated stromal cell response and new bone formation., Cell metabolism, 2010, 11

http://rdf.ncbi.nlm.nih.gov/pubmed/20142103

Jun. Guo, et.al., Suppression of Wnt signaling by Dkk1 attenuates PTH-mediated stromal cell response and new bone formation., Cell metabolism, 2010, 11

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Tg(Col1a1-Dkk1)1Hmk
  http://metadb.riken.jp/db/mgi_rdf/MGI:5818202

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal osteoclast physiology_Tg(Col1a1-Dkk1)1Hmk/?
  http://metadb.riken.jp/0001541B6FVBTgCol1a1Dkk11HmkTgCol1a1Dkk11HmkTgCol1a1Dkk11Hmk
• decreased bone trabecula number_Tg(Col1a1-Dkk1)1Hmk/?
  http://metadb.riken.jp/0010869B6FVBTgCol1a1Dkk11HmkTgCol1a1Dkk11HmkTgCol1a1Dkk11Hmk
• abnormal skeleton physiology_Tg(Col1a1-Dkk1)1Hmk/?
  http://metadb.riken.jp/0001533B6FVBTgCol1a1Dkk11HmkTgCol1a1Dkk11HmkTgCol1a1Dkk11Hmk
• decreased trabecular bone connectivity density_Tg(Col1a1-Dkk1)1Hmk/?
  http://metadb.riken.jp/0010933B6FVBTgCol1a1Dkk11HmkTgCol1a1Dkk11HmkTgCol1a1Dkk11Hmk
• abnormal bone mineralization_Tg(Col1a1-Dkk1)1Hmk/?
  http://metadb.riken.jp/0002896B6FVBTgCol1a1Dkk11HmkTgCol1a1Dkk11HmkTgCol1a1Dkk11Hmk
• decreased osteoblast cell number_Tg(Col1a1-Dkk1)1Hmk/?
  http://metadb.riken.jp/0004989B6FVBTgCol1a1Dkk11HmkTgCol1a1Dkk11HmkTgCol1a1Dkk11Hmk
• decreased bone strength_Tg(Col1a1-Dkk1)1Hmk/?
  http://metadb.riken.jp/0004991B6FVBTgCol1a1Dkk11HmkTgCol1a1Dkk11HmkTgCol1a1Dkk11Hmk
• decreased bone mineral density_Tg(Col1a1-Dkk1)1Hmk/?
  http://metadb.riken.jp/0000063B6FVBTgCol1a1Dkk11HmkTgCol1a1Dkk11HmkTgCol1a1Dkk11Hmk
• decreased bone ossification_Tg(Col1a1-Dkk1)1Hmk/?
  http://metadb.riken.jp/0020040B6FVBTgCol1a1Dkk11HmkTgCol1a1Dkk11HmkTgCol1a1Dkk11Hmk
• decreased trabecular bone volume_Tg(Col1a1-Dkk1)1Hmk/?
  http://metadb.riken.jp/0010879B6FVBTgCol1a1Dkk11HmkTgCol1a1Dkk11HmkTgCol1a1Dkk11Hmk
• increased osteoclast cell number_Tg(Col1a1-Dkk1)1Hmk/?
  http://metadb.riken.jp/0004984B6FVBTgCol1a1Dkk11HmkTgCol1a1Dkk11HmkTgCol1a1Dkk11Hmk
• impaired osteoblast differentiation_Tg(Col1a1-Dkk1)1Hmk/?
  http://metadb.riken.jp/0011711B6FVBTgCol1a1Dkk11HmkTgCol1a1Dkk11HmkTgCol1a1Dkk11Hmk
• insensitivity to parathyroid hormone_Tg(Col1a1-Dkk1)1Hmk/?
  http://metadb.riken.jp/0003497B6FVBTgCol1a1Dkk11HmkTgCol1a1Dkk11HmkTgCol1a1Dkk11Hmk
• increased bone trabecular spacing_Tg(Col1a1-Dkk1)1Hmk/?
  http://metadb.riken.jp/0013630B6FVBTgCol1a1Dkk11HmkTgCol1a1Dkk11HmkTgCol1a1Dkk11Hmk

class

http://purl.org/net/cito/citesAsAuthority

• Tg(Col1a1-Dkk1)1Hmk
  http://metadb.riken.jp/db/mgi_rdf/MGI:5818202

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD25795
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD25795