impaired branching involved in bronchus morphogenesis_Kras<tm4Tyj>/Kras<+>,Spry2<tm1.1Mrt>/Spry2<tm1.1Mrt>,Meox2<tm1(cre)Sor>/Meox2<+>

http://metadb.riken.jp/0011028I129P2OlaHsd129S4SvJaeSorFVBNKrastm4TyjKrasSpry2tm11MrtSpry2tm11MrtMeox2tm1creSorMeox2Meox2Spry2tm11MrtMeox2tm1creSorKrastm4TyjKras

impaired branching involved in bronchus morphogenesis_Kras<tm4Tyj>/Kras<+>,Spry2<tm1.1Mrt>/Spry2<tm1.1Mrt>,Meox2<tm1(cre)Sor>/Meox2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• Kirsten rat sarcoma viral oncogene homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96680
• sprouty homolog 2 (Drosophila)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1345138
• mesenchyme homeobox 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:103219

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Kras<tm4Tyj>/Kras<+>,Spry2<tm1.1Mrt>/Spry2<tm1.1Mrt>,Meox2<tm1(cre)Sor>/Meox2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Meox2<+>|Spry2<tm1.1Mrt>|Meox2<tm1(cre)Sor>|Kras<tm4Tyj>|Kras<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJaeSor * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired branching involved in bronchus morphogenesis
  http://purl.obolibrary.org/obo/MP_0011028

文献

http://purl.org/net/cito/citesAsAuthority

• Alice T. Shaw, et.al., Sprouty-2 regulates oncogenic K-ras in lung development and tumorigenesis., Genes & development, 2007, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/17369402