lethality at weaning, complete penetrance_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0

http://metadb.riken.jp/0011083I129P2OlaHsdC57BL6DBA2Slc39a4tm2GkaSlc39a4tm2GkaTgVilcreERT223Syr0TgVilcreERT223SyrSlc39a4tm2Gka

lethality at weaning, complete penetrance_Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 23, Sylvie Robine
  http://metadb.riken.jp/db/mgi_rdf/MGI:3053810
• solute carrier family 39 (zinc transporter), member 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:1919277

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Slc39a4<tm2Gka>/Slc39a4<tm2Gka>,Tg(Vil-cre/ERT2)23Syr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Vil-cre/ERT2)23Syr|Slc39a4<tm2Gka>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete lethality at weaning
  http://purl.obolibrary.org/obo/MP_0011083

文献

http://purl.org/net/cito/citesAsAuthority

• Jim. Geiser, et.al., A mouse model of acrodermatitis enteropathica: loss of intestine zinc transporter ZIP4 (Slc39a4) disrupts the stem cell niche and intestine integrity., PLoS genetics, 2012, 8
  http://rdf.ncbi.nlm.nih.gov/pubmed/22737083