postnatal lethality, complete penetrance_Foxa1<tm1Khk>/Foxa1<+>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0

http://metadb.riken.jp/0011085I129C57BL6CBASJLFoxa1tm1KhkFoxa1Foxa2tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw0Foxa1Foxa1tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw

postnatal lethality, complete penetrance_Foxa1<tm1Khk>/Foxa1<+>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 6, Christopher V E Wright
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177603
• forkhead box A2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1347476
• forkhead box A1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1347472

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Foxa1<tm1Khk>/Foxa1<+>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Foxa1<+>|Foxa1<tm1Khk>|Foxa2<tm1Khk>|Tg(Pdx1-cre)6Cvw

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CBA * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• Nan. Gao, et.al., Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development., Genes & development, 2008, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/19141476