Nan. Gao, et.al., Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development., Genes & development, 2008, 22

http://rdf.ncbi.nlm.nih.gov/pubmed/19141476

Nan. Gao, et.al., Dynamic regulation of Pdx1 enhancers by Foxa1 and Foxa2 is essential for pancreas development., Genes & development, 2008, 22

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Foxa1<tm1Khk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3831160

class

http://purl.org/net/cito/citesAsAuthority

• Foxa1<tm1Khk>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3831160

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• pancreas hypoplasia_Foxa1<tm1Khk>/Foxa1<tm1Khk>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0009111I129C57BL6CBASJLFoxa1tm1KhkFoxa1tm1KhkFoxa2tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw0Foxa2tm1KhkTgPdx1cre6CvwFoxa1tm1Khk
• pancreatic islet hypoplasia_Foxa1<tm1Khk>/Foxa1<tm1Khk>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0009169I129C57BL6CBASJLFoxa1tm1KhkFoxa1tm1KhkFoxa2tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw0Foxa2tm1KhkTgPdx1cre6CvwFoxa1tm1Khk
• pancreas hypoplasia_Foxa1<tm1Khk>/Foxa1<+>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0009111I129C57BL6CBASJLFoxa1tm1KhkFoxa1Foxa2tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw0Foxa1Foxa1tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw
• exocrine pancreas hypoplasia_Foxa1<tm1Khk>/Foxa1<+>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0005492I129C57BL6CBASJLFoxa1tm1KhkFoxa1Foxa2tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw0Foxa1Foxa1tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw
• exocrine pancreas hypoplasia_Foxa1<tm1Khk>/Foxa1<tm1Khk>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0005492I129C57BL6CBASJLFoxa1tm1KhkFoxa1tm1KhkFoxa2tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw0Foxa2tm1KhkTgPdx1cre6CvwFoxa1tm1Khk
• abnormal pancreas morphology_Foxa1<tm1Khk>/Foxa1<tm1Khk>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0001944I129C57BL6CBASJLFoxa1tm1KhkFoxa1tm1KhkFoxa2tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw0Foxa2tm1KhkTgPdx1cre6CvwFoxa1tm1Khk
• postnatal lethality, complete penetrance_Foxa1<tm1Khk>/Foxa1<tm1Khk>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0011085I129C57BL6CBASJLFoxa1tm1KhkFoxa1tm1KhkFoxa2tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw0Foxa2tm1KhkTgPdx1cre6CvwFoxa1tm1Khk
• abnormal pancreas development_Foxa1<tm1Khk>/Foxa1<tm1Khk>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0003934I129C57BL6CBASJLFoxa1tm1KhkFoxa1tm1KhkFoxa2tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw0Foxa2tm1KhkTgPdx1cre6CvwFoxa1tm1Khk
• pancreatic islet hypoplasia_Foxa1<tm1Khk>/Foxa1<+>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0009169I129C57BL6CBASJLFoxa1tm1KhkFoxa1Foxa2tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw0Foxa1Foxa1tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw
• postnatal lethality, complete penetrance_Foxa1<tm1Khk>/Foxa1<+>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0011085I129C57BL6CBASJLFoxa1tm1KhkFoxa1Foxa2tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw0Foxa1Foxa1tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw
• hyperglycemia_Foxa1<tm1Khk>/Foxa1<tm1Khk>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0001559I129C57BL6CBASJLFoxa1tm1KhkFoxa1tm1KhkFoxa2tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw0Foxa2tm1KhkTgPdx1cre6CvwFoxa1tm1Khk
• decreased pancreatic beta cell number_Foxa1<tm1Khk>/Foxa1<+>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0003339I129C57BL6CBASJLFoxa1tm1KhkFoxa1Foxa2tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw0Foxa1Foxa1tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw
• decreased pancreatic beta cell number_Foxa1<tm1Khk>/Foxa1<tm1Khk>,Foxa2<tm1Khk>/Foxa2<tm1Khk>,Tg(Pdx1-cre)6Cvw/0
  http://metadb.riken.jp/0003339I129C57BL6CBASJLFoxa1tm1KhkFoxa1tm1KhkFoxa2tm1KhkFoxa2tm1KhkTgPdx1cre6Cvw0Foxa2tm1KhkTgPdx1cre6CvwFoxa1tm1Khk