postnatal lethality, complete penetrance_Chuk<tm1Yhu>/Chuk<tm1Yhu>,Egfr<tm1Mag>/Egfr<tm1Mag>,Tg(KRT5-cre)5132Jlj/0

http://metadb.riken.jp/0011085I129C57BL6CD1Chuktm1YhuChuktm1YhuEgfrtm1MagEgfrtm1MagTgKRT5cre5132Jlj0Chuktm1YhuTgKRT5cre5132JljEgfrtm1Mag

postnatal lethality, complete penetrance_Chuk<tm1Yhu>/Chuk<tm1Yhu>,Egfr<tm1Mag>/Egfr<tm1Mag>,Tg(KRT5-cre)5132Jlj/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• conserved helix-loop-helix ubiquitous kinase
  http://metadb.riken.jp/db/mgi_rdf/MGI:99484
• epidermal growth factor receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:95294
• transgene insertion 5132, Jose Luis Jorcano
  http://metadb.riken.jp/db/mgi_rdf/MGI:3050066

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chuk<tm1Yhu>/Chuk<tm1Yhu>,Egfr<tm1Mag>/Egfr<tm1Mag>,Tg(KRT5-cre)5132Jlj/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Chuk<tm1Yhu>|Tg(KRT5-cre)5132Jlj|Egfr<tm1Mag>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6 * CD-1

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011085

文献

http://purl.org/net/cito/citesAsAuthority

• Bigang. Liu, et.al., IKKalpha is required to maintain skin homeostasis and prevent skin cancer., Cancer cell, 2008, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/18772111