postnatal lethality, incomplete penetrance_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>

http://metadb.riken.jp/0011086I129P2OlaHsdC3HeBFeJC57BL6JMcm3GtRRR002BygMcm3Mcm4chaos3Mcm4GtRRE056BygMcm3Mcm4GtRRE056BygMcm3GtRRR002BygMcm4chaos3

postnatal lethality, incomplete penetrance_Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• minichromosome maintenance complex component 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:103199
• minichromosome maintenance complex component 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:101845

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mcm3<Gt(RRR002)Byg>/Mcm3<+>,Mcm4<chaos3>/Mcm4<Gt(RRE056)Byg>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mcm3<+>|Mcm4<Gt(RRE056)Byg>|Mcm3<Gt(RRR002)Byg>|Mcm4<chaos3>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011086

文献

http://purl.org/net/cito/citesAsAuthority

• Chen-Hua. Chuang, et.al., Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress., PLoS genetics, 2010, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/20838603