postnatal lethality, incomplete penetrance_Mcm4<chaos3>/Mcm4<chaos3>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>

http://metadb.riken.jp/0011086I129P2OlaHsdC3HeBFeJC57BL6JMcm4chaos3Mcm4chaos3Mcm6GtYHD248BygMcm6Mcm4chaos3Mcm6GtYHD248BygMcm6

postnatal lethality, incomplete penetrance_Mcm4<chaos3>/Mcm4<chaos3>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• minichromosome maintenance complex component 6
  http://metadb.riken.jp/db/mgi_rdf/MGI:1298227
• minichromosome maintenance complex component 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:103199

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mcm4<chaos3>/Mcm4<chaos3>,Mcm6<Gt(YHD248)Byg>/Mcm6<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mcm4<chaos3>|Mcm6<Gt(YHD248)Byg>|Mcm6<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C3HeB/FeJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011086

文献

http://purl.org/net/cito/citesAsAuthority

• Chen-Hua. Chuang, et.al., Incremental genetic perturbations to MCM2-7 expression and subcellular distribution reveal exquisite sensitivity of mice to DNA replication stress., PLoS genetics, 2010, 6
  http://rdf.ncbi.nlm.nih.gov/pubmed/20838603