postnatal lethality, incomplete penetrance_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<+>

http://metadb.riken.jp/0011086I129P2OlaHsdC57BL6Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2Rps6kb2tm1GthoRps6kb1tm1GthoRps6kb2

postnatal lethality, incomplete penetrance_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ribosomal protein S6 kinase, polypeptide 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1927343
• ribosomal protein S6 kinase, polypeptide 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1270849

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rps6kb2<tm1Gtho>|Rps6kb1<tm1Gtho>|Rps6kb2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial postnatal lethality
  http://purl.obolibrary.org/obo/MP_0011086

文献

http://purl.org/net/cito/citesAsAuthority

• Mario. Pende, et.al., S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway., Molecular and cellular biology, 2004, 24
  http://rdf.ncbi.nlm.nih.gov/pubmed/15060135