Mario. Pende, et.al., S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway., Molecular and cellular biology, 2004, 24

http://rdf.ncbi.nlm.nih.gov/pubmed/15060135

Mario. Pende, et.al., S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway., Molecular and cellular biology, 2004, 24

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3771299

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• cyanosis_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/0001575I129P2OlaHsdC57BL6Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb2tm1Gtho
• decreased body size_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>
  http://metadb.riken.jp/0001265I129P2OlaHsdC57BL6Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb1tm1Gtho
• postnatal growth retardation_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/0001732B6129P2Rps6kb1tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb2tm1Gtho
• perinatal lethality, incomplete penetrance_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/0011090I129P2OlaHsdC57BL6Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb2tm1Gtho
• hypoxia_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/0005039I129P2OlaHsdC57BL6Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb2tm1Gtho
• postnatal lethality, incomplete penetrance_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/0011086B6129P2Rps6kb1tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb2tm1Gtho
• decreased litter size_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/0001935I129P2OlaHsdC57BL6Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb2tm1Gtho
• abnormal blood circulation_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/0002128I129P2OlaHsdC57BL6Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb2tm1Gtho
• neonatal lethality, incomplete penetrance_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/0011088B6129P2Rps6kb1tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb2tm1Gtho
• postnatal growth retardation_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>
  http://metadb.riken.jp/0001732I129P2OlaHsdC57BL6Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb1tm1Gtho
• postnatal growth retardation_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>
  http://metadb.riken.jp/0001732B6129P2Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb1tm1GthoRps6kb1tm1Gtho
• neonatal lethality, incomplete penetrance_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/0011088I129P2OlaHsdC57BL6Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb2tm1Gtho
• postnatal lethality, incomplete penetrance_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<+>
  http://metadb.riken.jp/0011086I129P2OlaHsdC57BL6Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2Rps6kb2tm1GthoRps6kb1tm1GthoRps6kb2
• abnormal heart morphology_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/0000266I129P2OlaHsdC57BL6Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb2tm1Gtho
• decreased embryo size_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>
  http://metadb.riken.jp/0001698I129P2OlaHsdC57BL6Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb1tm1Gtho
• hemorrhage_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/0001914I129P2OlaHsdC57BL6Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb2tm1Gtho
• postnatal growth retardation_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/0001732I129P2OlaHsdC57BL6Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb2tm1Gtho
• no abnormal phenotype detected_Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/0002169I129P2OlaHsdC57BL6Rps6kb2tm1GthoRps6kb2tm1GthoRps6kb2tm1Gtho
• postnatal lethality, incomplete penetrance_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/0011086I129P2OlaHsdC57BL6Rps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb2tm1Gtho
• perinatal lethality, incomplete penetrance_Rps6kb1<tm1Gtho>/Rps6kb1<tm1Gtho>,Rps6kb2<tm1Gtho>/Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/0011090B6129P2Rps6kb1tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb1tm1GthoRps6kb2tm1GthoRps6kb2tm1GthoRps6kb1tm1GthoRps6kb2tm1Gtho

class

http://purl.org/net/cito/citesAsAuthority

• Rps6kb2<tm1Gtho>
  http://metadb.riken.jp/db/mgi_rdf/MGI:3771299

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD05683
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD05683