neonatal lethality, complete penetrance_Igf1<tm1Arge>/Igf1<tm1Arge>,Igf1r<tm1Arge>/Igf1r<tm1Arge>

http://metadb.riken.jp/0011087EI129SSvEvorI129SSvEvC57BL6JorI129SSvEvMF1Igf1tm1ArgeIgf1tm1ArgeIgf1rtm1ArgeIgf1rtm1ArgeIgf1tm1ArgeIgf1rtm1Arge

neonatal lethality, complete penetrance_Igf1<tm1Arge>/Igf1<tm1Arge>,Igf1r<tm1Arge>/Igf1r<tm1Arge>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin-like growth factor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96432
• insulin-like growth factor I receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96433

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Igf1<tm1Arge>/Igf1<tm1Arge>,Igf1r<tm1Arge>/Igf1r<tm1Arge>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igf1<tm1Arge>|Igf1r<tm1Arge>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129S/SvEv) or (involves: 129S/SvEv * C57BL/6J) or (involves: 129S/SvEv * MF1)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete neonatal lethality
  http://purl.obolibrary.org/obo/MP_0011087

文献

http://purl.org/net/cito/citesAsAuthority

• J P. Liu, et.al., Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)., Cell, 1993, 75
  http://rdf.ncbi.nlm.nih.gov/pubmed/8402901