J P. Liu, et.al., Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)., Cell, 1993, 75

http://rdf.ncbi.nlm.nih.gov/pubmed/8402901

J P. Liu, et.al., Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)., Cell, 1993, 75

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Igf1<tm1Arge>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926485
• Igf1r<tm1Arge>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926486

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal hair follicle morphology_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0000377I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• maternal imprinting_Igf1<tm1Arge>/Igf1<tm1Arge>,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0003122EI129SSvEvorI129SSvEvC57BL6JorI129SSvEvMF1Igf1tm1ArgeIgf1tm1ArgeIgf2tm1RobIgf2Igf2Igf1tm1ArgeIgf2tm1Rob
• decreased birth weight_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0009674I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• thin epidermis stratum spinosum_Igf1<tm1Arge>/Igf1<tm1Arge>,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0001238EI129SSvEvorI129SSvEvC57BL6JorI129SSvEvMF1Igf1tm1ArgeIgf1tm1ArgeIgf2tm1RobIgf2Igf2Igf1tm1ArgeIgf2tm1Rob
• atelectasis_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0001177I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• decreased body weight_Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0001262I129SSvEvIgf2tm1RobIgf2Igf2Igf2tm1Rob
• maternal imprinting_Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0003122I129SSvEvIgf2tm1RobIgf2Igf2Igf2tm1Rob
• delayed bone ossification_Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0000060I129SSvEvIgf2tm1RobIgf2Igf2Igf2tm1Rob
• abnormal nervous system morphology_Igf1r<tm1Arge>/Igf1r<tm1Arge>,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0003632I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf2tm1RobIgf2Igf1rtm1ArgeIgf2tm1RobIgf2
• abnormal spinal cord morphology_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0000955I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• delayed bone ossification_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0000060I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• respiratory failure_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0001953I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• delayed bone ossification_Igf1<tm1Arge>/Igf1<tm1Arge>
  http://metadb.riken.jp/0000060E129SSvEvIgf1tm1ArgeorI129SSvEvC57BL6JorI129SSvEvMF1Igf1tm1ArgeIgf1tm1ArgeIgf1tm1Arge
• respiratory failure_Igf1<tm1Arge>/Igf1<tm1Arge>,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0001953EI129SSvEvorI129SSvEvC57BL6JorI129SSvEvMF1Igf1tm1ArgeIgf1tm1ArgeIgf2tm1RobIgf2Igf2Igf1tm1ArgeIgf2tm1Rob
• maternal imprinting_Igf1r<tm1Arge>/Igf1r<tm1Arge>,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0003122I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf2tm1RobIgf2Igf1rtm1ArgeIgf2tm1RobIgf2
• neonatal lethality, complete penetrance_Igf1<tm1Arge>/Igf1<tm1Arge>,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0011087EI129SSvEvorI129SSvEvC57BL6JorI129SSvEvMF1Igf1tm1ArgeIgf1tm1ArgeIgf2tm1RobIgf2Igf2Igf1tm1ArgeIgf2tm1Rob
• abnormal postnatal growth/weight/body size_Igf1r<tm1Arge>/Igf1r<+>
  http://metadb.riken.jp/0002089I129SSvEvIgf1rtm1ArgeIgf1rIgf1rtm1ArgeIgf1r
• decreased hair follicle number_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0000379I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• postnatal growth retardation_Igf1<tm1Arge>/Igf1<tm1Arge>
  http://metadb.riken.jp/0001732E129SSvEvIgf1tm1ArgeorI129SSvEvC57BL6JorI129SSvEvMF1Igf1tm1ArgeIgf1tm1ArgeIgf1tm1Arge
• decreased body size_Igf1<tm1Arge>/Igf1<tm1Arge>
  http://metadb.riken.jp/0001265E129SSvEvIgf1tm1ArgeorI129SSvEvC57BL6JorI129SSvEvMF1Igf1tm1ArgeIgf1tm1ArgeIgf1tm1Arge
• respiratory failure_Igf1<tm1Arge>/Igf1<tm1Arge>,Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0001953EI129SSvEvorI129SSvEvC57BL6JorI129SSvEvMF1Igf1tm1ArgeIgf1tm1ArgeIgf1rtm1ArgeIgf1rtm1ArgeIgf1tm1ArgeIgf1rtm1Arge
• thin epidermis_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0001218I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• muscle hypoplasia_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0000734I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• delayed bone ossification_Igf1<tm1Arge>/Igf1<tm1Arge>,Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0000060EI129SSvEvorI129SSvEvC57BL6JorI129SSvEvMF1Igf1tm1ArgeIgf1tm1ArgeIgf1rtm1ArgeIgf1rtm1ArgeIgf1tm1ArgeIgf1rtm1Arge
• decreased birth weight_Igf1<tm1Arge>/Igf1<tm1Arge>,Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0009674EI129SSvEvorI129SSvEvC57BL6JorI129SSvEvMF1Igf1tm1ArgeIgf1tm1ArgeIgf1rtm1ArgeIgf1rtm1ArgeIgf1tm1ArgeIgf1rtm1Arge
• cyanosis_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0001575I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• neonatal lethality, complete penetrance_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0011087I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• decreased oligodendrocyte progenitor number_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0000954I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• delayed bone ossification_Igf1<tm1Arge>/Igf1<tm1Arge>,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0000060EI129SSvEvorI129SSvEvC57BL6JorI129SSvEvMF1Igf1tm1ArgeIgf1tm1ArgeIgf2tm1RobIgf2Igf2Igf1tm1ArgeIgf2tm1Rob
• neonatal lethality, complete penetrance_Igf1r<tm1Arge>/Igf1r<tm1Arge>,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0011087I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf2tm1RobIgf2Igf1rtm1ArgeIgf2tm1RobIgf2
• decreased birth weight_Igf1r<tm1Arge>/Igf1r<tm1Arge>,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0009674I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf2tm1RobIgf2Igf1rtm1ArgeIgf2tm1RobIgf2
• abnormal epidermal layer morphology_Igf1r<tm1Arge>/Igf1r<tm1Arge>,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0001216I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf2tm1RobIgf2Igf1rtm1ArgeIgf2tm1RobIgf2
• translucent skin_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0001201I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• small hair follicles_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0000380I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• neonatal lethality, complete penetrance_Igf1<tm1Arge>/Igf1<tm1Arge>
  http://metadb.riken.jp/0011087E129SSvEvIgf1tm1ArgeorI129SSvEvC57BL6JorI129SSvEvMF1Igf1tm1ArgeIgf1tm1ArgeIgf1tm1Arge
• respiratory failure_Igf1r<tm1Arge>/Igf1r<tm1Arge>,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0001953I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf2tm1RobIgf2Igf1rtm1ArgeIgf2tm1RobIgf2
• neonatal lethality, complete penetrance_Igf1<tm1Arge>/Igf1<tm1Arge>,Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0011087EI129SSvEvorI129SSvEvC57BL6JorI129SSvEvMF1Igf1tm1ArgeIgf1tm1ArgeIgf1rtm1ArgeIgf1rtm1ArgeIgf1tm1ArgeIgf1rtm1Arge
• thin epidermis stratum spinosum_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0001238I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• decreased birth weight_Igf1<tm1Arge>/Igf1<tm1Arge>,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0009674EI129SSvEvorI129SSvEvC57BL6JorI129SSvEvMF1Igf1tm1ArgeIgf1tm1ArgeIgf2tm1RobIgf2Igf2Igf1tm1ArgeIgf2tm1Rob
• abnormal brainstem morphology_Igf1r<tm1Arge>/Igf1r<tm1Arge>
  http://metadb.riken.jp/0005277I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf1rtm1Arge
• delayed bone ossification_Igf1r<tm1Arge>/Igf1r<tm1Arge>,Igf2<tm1Rob>/Igf2<+>
  http://metadb.riken.jp/0000060I129SSvEvIgf1rtm1ArgeIgf1rtm1ArgeIgf2tm1RobIgf2Igf1rtm1ArgeIgf2tm1RobIgf2

class

http://purl.org/net/cito/citesAsAuthority

• Igf1<tm1Arge>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926485
• Igf1r<tm1Arge>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926486