neonatal lethality, complete penetrance_Hmgb1<tm1.1Ttg>/Hmgb1<tm1.2Ttg>,Tg(CAG-cre)13Miya/0

http://metadb.riken.jp/0011087I129P2OlaHsdC57BL6Hmgb1tm11TtgHmgb1tm12TtgTgCAGcre13Miya0Hmgb1tm12TtgHmgb1tm11TtgTgCAGcre13Miya

neonatal lethality, complete penetrance_Hmgb1<tm1.1Ttg>/Hmgb1<tm1.2Ttg>,Tg(CAG-cre)13Miya/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• high mobility group box 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96113
• transgene insertion 13, Jun-ichi Miyazaki
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176594

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hmgb1<tm1.1Ttg>/Hmgb1<tm1.2Ttg>,Tg(CAG-cre)13Miya/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hmgb1<tm1.2Ttg>|Hmgb1<tm1.1Ttg>|Tg(CAG-cre)13Miya

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete neonatal lethality
  http://purl.obolibrary.org/obo/MP_0011087

文献

http://purl.org/net/cito/citesAsAuthority

• Hideyuki. Yanai, et.al., Conditional ablation of HMGB1 in mice reveals its protective function against endotoxemia and bacterial infection., Proceedings of the National Academy of Sciences of the United States of America, 2013, 110
  http://rdf.ncbi.nlm.nih.gov/pubmed/24302768