neonatal lethality, complete penetrance_Eif2s1<tm1Rjk>/Eif2s1<tm1Rjk>,Ppp1r15b<tm1Dron>/Ppp1r15b<tm1Dron>

http://metadb.riken.jp/0011087I129P2OlaHsdEif2s1tm1RjkEif2s1tm1RjkPpp1r15btm1DronPpp1r15btm1DronPpp1r15btm1DronEif2s1tm1Rjk

neonatal lethality, complete penetrance_Eif2s1<tm1Rjk>/Eif2s1<tm1Rjk>,Ppp1r15b<tm1Dron>/Ppp1r15b<tm1Dron>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein phosphatase 1, regulatory (inhibitor) subunit 15b
  http://metadb.riken.jp/db/mgi_rdf/MGI:2444211
• eukaryotic translation initiation factor 2, subunit 1 alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:95299

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Eif2s1<tm1Rjk>/Eif2s1<tm1Rjk>,Ppp1r15b<tm1Dron>/Ppp1r15b<tm1Dron>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ppp1r15b<tm1Dron>|Eif2s1<tm1Rjk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete neonatal lethality
  http://purl.obolibrary.org/obo/MP_0011087

文献

http://purl.org/net/cito/citesAsAuthority

• Heather P. Harding, et.al., Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2alpha) dephosphorylation in mammalian development., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19181853