neonatal lethality, complete penetrance_Prkar1a<tm1.2Lsk>/Prkar1a<tm1.2Lsk>,Tg(Col1a1-cre)1Kry/0

http://metadb.riken.jp/0011087I129S1Sv129X1SvJFVBNPrkar1atm12LskPrkar1atm12LskTgCol1a1cre1Kry0TgCol1a1cre1KryPrkar1atm12Lsk

neonatal lethality, complete penetrance_Prkar1a<tm1.2Lsk>/Prkar1a<tm1.2Lsk>,Tg(Col1a1-cre)1Kry/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein kinase, cAMP dependent regulatory, type I, alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:104878
• transgene insertion 1, Gerard Karsenty
  http://metadb.riken.jp/db/mgi_rdf/MGI:3041865

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prkar1a<tm1.2Lsk>/Prkar1a<tm1.2Lsk>,Tg(Col1a1-cre)1Kry/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Col1a1-cre)1Kry|Prkar1a<tm1.2Lsk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete neonatal lethality
  http://purl.obolibrary.org/obo/MP_0011087

文献

http://purl.org/net/cito/citesAsAuthority

• Sam D. Molyneux, et.al., Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20697156