neonatal lethality, complete penetrance_Rr27<tm1Tilg>/Rr27<+>,Igf2<tm1Rob>/Igf2<+>,Igf2r<tm1Stw>/Igf2r<+>

http://metadb.riken.jp/0011087I129SSvEv129S1SvC57BL6JRr27tm1TilgRr27Igf2tm1RobIgf2Igf2rtm1StwIgf2rIgf2tm1RobRr27Igf2rtm1StwRr27tm1TilgIgf2Igf2r

neonatal lethality, complete penetrance_Rr27<tm1Tilg>/Rr27<+>,Igf2<tm1Rob>/Igf2<+>,Igf2r<tm1Stw>/Igf2r<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin-like growth factor 2 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96435
• insulin-like growth factor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:96434
• regulatory region 27
  http://metadb.riken.jp/db/mgi_rdf/MGI:5489785

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rr27<tm1Tilg>/Rr27<+>,Igf2<tm1Rob>/Igf2<+>,Igf2r<tm1Stw>/Igf2r<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Igf2<tm1Rob>|Rr27<+>|Igf2r<tm1Stw>|Rr27<tm1Tilg>|Igf2<+>|Igf2r<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S1/Sv * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete neonatal lethality
  http://purl.obolibrary.org/obo/MP_0011087

文献

http://purl.org/net/cito/citesAsAuthority

• J. Eggenschwiler, et.al., Mouse mutant embryos overexpressing IGF-II exhibit phenotypic features of the Beckwith-Wiedemann and Simpson-Golabi-Behmel syndromes., Genes & development, 1997, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/9389646