neonatal lethality, complete penetrance_Meox2<tm1(cre)Sor>/Meox2<+>,Mfn1<tm1Dcc>/Mfn1<tm2Dcc>,Mfn2<tm1Dcc>/Mfn2<tm3Dcc>

http://metadb.riken.jp/0011087I129SSvEv129S4SvJaeSorBlackSwissMeox2tm1creSorMeox2Mfn1tm1DccMfn1tm2DccMfn2tm1DccMfn2tm3DccMfn2tm1DccMeox2tm1creSorMfn1tm2DccMfn1tm1DccMfn2tm3DccMeox2

neonatal lethality, complete penetrance_Meox2<tm1(cre)Sor>/Meox2<+>,Mfn1<tm1Dcc>/Mfn1<tm2Dcc>,Mfn2<tm1Dcc>/Mfn2<tm3Dcc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• mitofusin 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2442230
• mesenchyme homeobox 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:103219
• mitofusin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1914664

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Meox2<tm1(cre)Sor>/Meox2<+>,Mfn1<tm1Dcc>/Mfn1<tm2Dcc>,Mfn2<tm1Dcc>/Mfn2<tm3Dcc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mfn2<tm1Dcc>|Meox2<tm1(cre)Sor>|Mfn1<tm2Dcc>|Mfn1<tm1Dcc>|Mfn2<tm3Dcc>|Meox2<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S4/SvJaeSor * Black Swiss

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete neonatal lethality
  http://purl.obolibrary.org/obo/MP_0011087

文献

http://purl.org/net/cito/citesAsAuthority

• Hsiuchen. Chen, et.al., Mitochondrial fusion protects against neurodegeneration in the cerebellum., Cell, 2007, 130
  http://rdf.ncbi.nlm.nih.gov/pubmed/17693261