neonatal lethality, incomplete penetrance_Fgfr3<tm4Cxd>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/0

http://metadb.riken.jp/0011088I129S6SvEvTacC57BL6NIHBlackSwissSJLFgfr3tm4CxdFgfr3TgCol2a1cre1Bhr0Fgfr3TgCol2a1cre1BhrFgfr3tm4Cxd

neonatal lethality, incomplete penetrance_Fgfr3<tm4Cxd>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• fibroblast growth factor receptor 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:95524
• transgene insertion 1, Richard R Behringer
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176069

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fgfr3<tm4Cxd>/Fgfr3<+>,Tg(Col2a1-cre)1Bhr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fgfr3<+>|Tg(Col2a1-cre)1Bhr|Fgfr3<tm4Cxd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * NIH Black Swiss * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• partial neonatal lethality
  http://purl.obolibrary.org/obo/MP_0011088

文献

http://purl.org/net/cito/citesAsAuthority

• T. Iwata, et.al., A neonatal lethal mutation in FGFR3 uncouples proliferation and differentiation of growth plate chondrocytes in embryos., Human molecular genetics, 2000, 9
  http://rdf.ncbi.nlm.nih.gov/pubmed/10861287