perinatal lethality, complete penetrance_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0

http://metadb.riken.jp/0011089I129S1Sv129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorIhhtm1AmcIhhtm1AmcTgCol2a1cre3Amc0Ihhtm1AmcGtROSA26SorTgCol2a1cre3AmcGtROSA26Sortm2Gli2Flng

perinatal lethality, complete penetrance_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• Indian hedgehog
  http://metadb.riken.jp/db/mgi_rdf/MGI:96533
• transgene insertion 3, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176260

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ihh<tm1Amc>|Gt(ROSA)26Sor<+>|Tg(Col2a1-cre)3Amc|Gt(ROSA)26Sor<tm2(Gli2*)Flng>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete perinatal lethality
  http://purl.obolibrary.org/obo/MP_0011089

文献

http://purl.org/net/cito/citesAsAuthority

• Kyu Sang. Joeng, et.al., The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization., Development (Cambridge, England), 2009, 136
  http://rdf.ncbi.nlm.nih.gov/pubmed/19906844