Kyu Sang. Joeng, et.al., The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization., Development (Cambridge, England), 2009, 136

http://rdf.ncbi.nlm.nih.gov/pubmed/19906844

Kyu Sang. Joeng, et.al., The Gli2 transcriptional activator is a crucial effector for Ihh signaling in osteoblast development and cartilage vascularization., Development (Cambridge, England), 2009, 136

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm2(Gli2*)Flng>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4414671

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal bone marrow cavity morphology_Gli3<Xt-J>/Gli3<Xt-J>,Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0000065I129S1Sv129X1SvJC3HHeJGli3XtJGli3XtJIhhtm1AmcIhhtm1AmcGli3XtJIhhtm1Amc
• abnormal cartilage development_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0000164I129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorTgCol2a1cre3Amc0GtROSA26SorGtROSA26Sortm2Gli2FlngTgCol2a1cre3Amc
• abnormal long bone hypertrophic chondrocyte zone_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0000165I129S1Sv129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorIhhtm1AmcIhhtm1AmcGtROSA26Sortm2Gli2FlngIhhtm1AmcGtROSA26Sor
• abnormal long bone hypertrophic chondrocyte zone_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0000165I129S1Sv129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorIhhtm1AmcIhhtm1AmcTgCol2a1cre3Amc0Ihhtm1AmcGtROSA26SorTgCol2a1cre3AmcGtROSA26Sortm2Gli2Flng
• short limbs_Gli3<Xt-J>/Gli3<Xt-J>,Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0000547I129S1Sv129X1SvJC3HHeJGli3XtJGli3XtJGtROSA26Sortm2Gli2FlngGtROSA26SorIhhtm1AmcIhhtm1AmcTgCol2a1cre3Amc0GtROSA26SorGli3XtJIhhtm1AmcTgCol2a1cre3AmcGtROSA26Sortm2Gli2Flng
• decreased body size_Gli3<Xt-J>/Gli3<Xt-J>,Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0001265I129S1Sv129X1SvJC3HHeJGli3XtJGli3XtJGtROSA26Sortm2Gli2FlngGtROSA26SorIhhtm1AmcIhhtm1AmcTgCol2a1cre3Amc0GtROSA26SorGli3XtJIhhtm1AmcTgCol2a1cre3AmcGtROSA26Sortm2Gli2Flng
他16件を見る
• decreased body size_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0001265I129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorTgCol2a1cre3Amc0GtROSA26SorGtROSA26Sortm2Gli2FlngTgCol2a1cre3Amc
• increased width of hypertrophic chondrocyte zone_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0003408I129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorTgCol2a1cre3Amc0GtROSA26SorGtROSA26Sortm2Gli2FlngTgCol2a1cre3Amc
• decreased width of hypertrophic chondrocyte zone_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0003409I129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorTgCol2a1cre3Amc0GtROSA26SorGtROSA26Sortm2Gli2FlngTgCol2a1cre3Amc
• abnormal long bone epiphyseal plate proliferative zone_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0003662I129S1Sv129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorIhhtm1AmcIhhtm1AmcGtROSA26Sortm2Gli2FlngIhhtm1AmcGtROSA26Sor
• abnormal long bone epiphyseal plate proliferative zone_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0003662I129S1Sv129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorIhhtm1AmcIhhtm1AmcTgCol2a1cre3Amc0Ihhtm1AmcGtROSA26SorTgCol2a1cre3AmcGtROSA26Sortm2Gli2Flng
• abnormal long bone epiphyseal plate proliferative zone_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0003662I129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorTgCol2a1cre3Amc0GtROSA26SorGtROSA26Sortm2Gli2FlngTgCol2a1cre3Amc
• abnormal long bone diaphysis morphology_Gli3<Xt-J>/Gli3<Xt-J>,Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0004214I129S1Sv129X1SvJC3HHeJGli3XtJGli3XtJGtROSA26Sortm2Gli2FlngGtROSA26SorIhhtm1AmcIhhtm1AmcTgCol2a1cre3Amc0GtROSA26SorGli3XtJIhhtm1AmcTgCol2a1cre3AmcGtROSA26Sortm2Gli2Flng
• decreased length of long bones_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0004686I129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorTgCol2a1cre3Amc0GtROSA26SorGtROSA26Sortm2Gli2FlngTgCol2a1cre3Amc
• abnormal perichondrium morphology_Gli3<Xt-J>/Gli3<Xt-J>,Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0006322I129S1Sv129X1SvJC3HHeJGli3XtJGli3XtJIhhtm1AmcIhhtm1AmcGli3XtJIhhtm1Amc
• abnormal perichondrium morphology_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0006322I129S1Sv129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorIhhtm1AmcIhhtm1AmcTgCol2a1cre3Amc0Ihhtm1AmcGtROSA26SorTgCol2a1cre3AmcGtROSA26Sortm2Gli2Flng
• disorganized long bone epiphyseal plate_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0006397I129S1Sv129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorIhhtm1AmcIhhtm1AmcGtROSA26Sortm2Gli2FlngIhhtm1AmcGtROSA26Sor
• disorganized long bone epiphyseal plate_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0006397I129S1Sv129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorIhhtm1AmcIhhtm1AmcTgCol2a1cre3Amc0Ihhtm1AmcGtROSA26SorTgCol2a1cre3AmcGtROSA26Sortm2Gli2Flng
• abnormal osteoblast differentiation_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>
  http://metadb.riken.jp/0008395I129S1Sv129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorIhhtm1AmcIhhtm1AmcGtROSA26Sortm2Gli2FlngIhhtm1AmcGtROSA26Sor
• abnormal osteoblast differentiation_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0008395I129S1Sv129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorIhhtm1AmcIhhtm1AmcTgCol2a1cre3Amc0Ihhtm1AmcGtROSA26SorTgCol2a1cre3AmcGtROSA26Sortm2Gli2Flng
• perinatal lethality, complete penetrance_Gli3<Xt-J>/Gli3<Xt-J>,Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0011089I129S1Sv129X1SvJC3HHeJGli3XtJGli3XtJGtROSA26Sortm2Gli2FlngGtROSA26SorIhhtm1AmcIhhtm1AmcTgCol2a1cre3Amc0GtROSA26SorGli3XtJIhhtm1AmcTgCol2a1cre3AmcGtROSA26Sortm2Gli2Flng
• perinatal lethality, complete penetrance_Gt(ROSA)26Sor<tm2(Gli2*)Flng>/Gt(ROSA)26Sor<+>,Ihh<tm1Amc>/Ihh<tm1Amc>,Tg(Col2a1-cre)3Amc/0
  http://metadb.riken.jp/0011089I129S1Sv129X1SvJGtROSA26Sortm2Gli2FlngGtROSA26SorIhhtm1AmcIhhtm1AmcTgCol2a1cre3Amc0Ihhtm1AmcGtROSA26SorTgCol2a1cre3AmcGtROSA26Sortm2Gli2Flng

class

http://purl.org/net/cito/citesAsAuthority

• Gt(ROSA)26Sor<tm2(Gli2*)Flng>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4414671