perinatal lethality, complete penetrance_Rbfox1<tm1.1Dblk>/Rbfox1<tm1.1Dblk>,Rbfox2<tm1.1Dblk>/Rbfox2<tm1.1Dblk>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0011089I129S2SvPasC57BL6C57BL6JSJLRbfox1tm11DblkRbfox1tm11DblkRbfox2tm11DblkRbfox2tm11DblkTgNescre1Kln0TgNescre1KlnRbfox1tm11DblkRbfox2tm11Dblk

perinatal lethality, complete penetrance_Rbfox1<tm1.1Dblk>/Rbfox1<tm1.1Dblk>,Rbfox2<tm1.1Dblk>/Rbfox2<tm1.1Dblk>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172
• RNA binding protein, fox-1 homolog (C. elegans) 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926224
• RNA binding protein, fox-1 homolog (C. elegans) 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1933973

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rbfox1<tm1.1Dblk>/Rbfox1<tm1.1Dblk>,Rbfox2<tm1.1Dblk>/Rbfox2<tm1.1Dblk>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nes-cre)1Kln|Rbfox1<tm1.1Dblk>|Rbfox2<tm1.1Dblk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * C57BL/6J * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete perinatal lethality
  http://purl.obolibrary.org/obo/MP_0011089

文献

http://purl.org/net/cito/citesAsAuthority

• Lauren T. Gehman, et.al., The splicing regulator Rbfox2 is required for both cerebellar development and mature motor function., Genes & development, 2012, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/22357600