prenatal lethality, complete penetrance_Paxx<em1Spj>/Paxx<em1Spj>,Lig4<tm1Fwa>/Lig4<tm1Fwa>

http://metadb.riken.jp/0011091I129S6SvEvTacC57BL6C57BL6NTacPaxxem1SpjPaxxem1SpjLig4tm1FwaLig4tm1FwaPaxxem1SpjLig4tm1Fwa

prenatal lethality, complete penetrance_Paxx<em1Spj>/Paxx<em1Spj>,Lig4<tm1Fwa>/Lig4<tm1Fwa>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ligase IV, DNA, ATP-dependent
  http://metadb.riken.jp/db/mgi_rdf/MGI:1335098
• non-homologous end joining factor
  http://metadb.riken.jp/db/mgi_rdf/MGI:2442831

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Paxx<em1Spj>/Paxx<em1Spj>,Lig4<tm1Fwa>/Lig4<tm1Fwa>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Paxx<em1Spj>|Lig4<tm1Fwa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * C57BL/6NTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete prenatal lethality
  http://purl.obolibrary.org/obo/MP_0011091

文献

http://purl.org/net/cito/citesAsAuthority

• Gabriel. Balmus, et.al., Synthetic lethality between PAXX and XLF in mammalian development., Genes & development, 2016, 30
  http://rdf.ncbi.nlm.nih.gov/pubmed/27798842