embryonic lethality, complete penetrance_Apc<tm1Rak>/Apc<+>,Ctnnb1<tm1.2Wvv>/Ctnnb1<+>

http://metadb.riken.jp/0011092I129P2OlaHsdC57BL6JApctm1RakApcCtnnb1tm12WvvCtnnb1Ctnnb1Apctm1RakApcCtnnb1tm12Wvv

embryonic lethality, complete penetrance_Apc<tm1Rak>/Apc<+>,Ctnnb1<tm1.2Wvv>/Ctnnb1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• catenin (cadherin associated protein), beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88276
• adenomatosis polyposis coli
  http://metadb.riken.jp/db/mgi_rdf/MGI:88039

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apc<tm1Rak>/Apc<+>,Ctnnb1<tm1.2Wvv>/Ctnnb1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ctnnb1<+>|Apc<tm1Rak>|Apc<+>|Ctnnb1<tm1.2Wvv>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011092

文献

http://purl.org/net/cito/citesAsAuthority

• Wendy. van Veelen, et.al., β-catenin tyrosine 654 phosphorylation increases Wnt signalling and intestinal tumorigenesis., Gut, 2011, 60
  http://rdf.ncbi.nlm.nih.gov/pubmed/21307168