embryonic lethality, complete penetrance_Chd1<tm1c(KOMP)Rsan>/Chd1<tm1c(KOMP)Rsan>,Tg(Sox2-cre)1Amc/?

http://metadb.riken.jp/0011092I129P2OlaHsdC57BL6JCBAChd1tm1cKOMPRsanChd1tm1cKOMPRsanTgSox2cre1AmcTgSox2cre1AmcChd1tm1cKOMPRsan

embryonic lethality, complete penetrance_Chd1<tm1c(KOMP)Rsan>/Chd1<tm1c(KOMP)Rsan>,Tg(Sox2-cre)1Amc/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Andrew P McMahon
  http://metadb.riken.jp/db/mgi_rdf/MGI:2656537
• chromodomain helicase DNA binding protein 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88393

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chd1<tm1c(KOMP)Rsan>/Chd1<tm1c(KOMP)Rsan>,Tg(Sox2-cre)1Amc/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Sox2-cre)1Amc|Chd1<tm1c(KOMP)Rsan>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6J * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011092

文献

http://purl.org/net/cito/citesAsAuthority

• Marcela. Guzman-Ayala, et.al., Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast., Development (Cambridge, England), 2015, 142
  http://rdf.ncbi.nlm.nih.gov/pubmed/25480920