Marcela. Guzman-Ayala, et.al., Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast., Development (Cambridge, England), 2015, 142

http://rdf.ncbi.nlm.nih.gov/pubmed/25480920

Marcela. Guzman-Ayala, et.al., Chd1 is essential for the high transcriptional output and rapid growth of the mouse epiblast., Development (Cambridge, England), 2015, 142

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Chd1<tm1b(KOMP)Rsan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5637386
• Chd1<tm1c(KOMP)Rsan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5637385

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• abnormal embryo development_Chd1<tm1b(KOMP)Rsan>/Chd1<tm1b(KOMP)Rsan>
  http://metadb.riken.jp/0001672I129P2OlaHsdC57BL6JChd1tm1bKOMPRsanChd1tm1bKOMPRsanChd1tm1bKOMPRsan
• failure to gastrulate_Chd1<tm1b(KOMP)Rsan>/Chd1<tm1b(KOMP)Rsan>
  http://metadb.riken.jp/0001696I129P2OlaHsdC57BL6JChd1tm1bKOMPRsanChd1tm1bKOMPRsanChd1tm1bKOMPRsan
• increased embryonic epiblast cell apoptosis_Chd1<tm1b(KOMP)Rsan>/Chd1<tm1b(KOMP)Rsan>
  http://metadb.riken.jp/0011191I129P2OlaHsdC57BL6JChd1tm1bKOMPRsanChd1tm1bKOMPRsanChd1tm1bKOMPRsan
• small embryonic epiblast_Chd1<tm1b(KOMP)Rsan>/Chd1<tm1b(KOMP)Rsan>
  http://metadb.riken.jp/0011189I129P2OlaHsdC57BL6JChd1tm1bKOMPRsanChd1tm1bKOMPRsanChd1tm1bKOMPRsan
• abnormal developmental patterning_Chd1<tm1b(KOMP)Rsan>/Chd1<tm1b(KOMP)Rsan>
  http://metadb.riken.jp/0002084I129P2OlaHsdC57BL6JChd1tm1bKOMPRsanChd1tm1bKOMPRsanChd1tm1bKOMPRsan
• absent anterior visceral endoderm_Chd1<tm1b(KOMP)Rsan>/Chd1<tm1b(KOMP)Rsan>
  http://metadb.riken.jp/0012159I129P2OlaHsdC57BL6JChd1tm1bKOMPRsanChd1tm1bKOMPRsanChd1tm1bKOMPRsan
• embryonic lethality, complete penetrance_Chd1<tm1c(KOMP)Rsan>/Chd1<tm1c(KOMP)Rsan>,Tg(Sox2-cre)1Amc/?
  http://metadb.riken.jp/0011092I129P2OlaHsdC57BL6JCBAChd1tm1cKOMPRsanChd1tm1cKOMPRsanTgSox2cre1AmcTgSox2cre1AmcChd1tm1cKOMPRsan
• decreased embryo size_Chd1<tm1b(KOMP)Rsan>/Chd1<tm1b(KOMP)Rsan>
  http://metadb.riken.jp/0001698I129P2OlaHsdC57BL6JChd1tm1bKOMPRsanChd1tm1bKOMPRsanChd1tm1bKOMPRsan
• abnormal mesoderm development_Chd1<tm1b(KOMP)Rsan>/Chd1<tm1b(KOMP)Rsan>
  http://metadb.riken.jp/0001680I129P2OlaHsdC57BL6JChd1tm1bKOMPRsanChd1tm1bKOMPRsanChd1tm1bKOMPRsan
• abnormal cell cycle_Chd1<tm1b(KOMP)Rsan>/Chd1<tm1b(KOMP)Rsan>
  http://metadb.riken.jp/0003077I129P2OlaHsdC57BL6JChd1tm1bKOMPRsanChd1tm1bKOMPRsanChd1tm1bKOMPRsan
• absent extraembryonic ectoderm_Chd1<tm1b(KOMP)Rsan>/Chd1<tm1b(KOMP)Rsan>
  http://metadb.riken.jp/0002583I129P2OlaHsdC57BL6JChd1tm1bKOMPRsanChd1tm1bKOMPRsanChd1tm1bKOMPRsan
• abnormal rostral-caudal axis patterning_Chd1<tm1b(KOMP)Rsan>/Chd1<tm1b(KOMP)Rsan>
  http://metadb.riken.jp/0005221I129P2OlaHsdC57BL6JChd1tm1bKOMPRsanChd1tm1bKOMPRsanChd1tm1bKOMPRsan
• embryonic lethality, complete penetrance_Chd1<tm1b(KOMP)Rsan>/Chd1<tm1b(KOMP)Rsan>
  http://metadb.riken.jp/0011092I129P2OlaHsdC57BL6JChd1tm1bKOMPRsanChd1tm1bKOMPRsanChd1tm1bKOMPRsan

class

http://purl.org/net/cito/citesAsAuthority

• Chd1<tm1b(KOMP)Rsan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5637386
• Chd1<tm1c(KOMP)Rsan>
  http://metadb.riken.jp/db/mgi_rdf/MGI:5637385