embryonic lethality, complete penetrance_Ctnnb1<tm2Kem>/Ctnnb1<tm2Kem>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0

http://metadb.riken.jp/0011092I129S1Sv129S4SvJae129X1SvJBALBcC57BL6FVBNCtnnb1tm2KemCtnnb1tm2KemPtentm1HwuPtentm1HwuTgCdh5cre7Mlia0Ptentm1HwuTgCdh5cre7MliaCtnnb1tm2Kem

embryonic lethality, complete penetrance_Ctnnb1<tm2Kem>/Ctnnb1<tm2Kem>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• catenin (cadherin associated protein), beta 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88276
• transgene insertion 7, M Luisa Iruela-Arispe
  http://metadb.riken.jp/db/mgi_rdf/MGI:3620559
• phosphatase and tensin homolog
  http://metadb.riken.jp/db/mgi_rdf/MGI:109583

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ctnnb1<tm2Kem>/Ctnnb1<tm2Kem>,Pten<tm1Hwu>/Pten<tm1Hwu>,Tg(Cdh5-cre)7Mlia/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pten<tm1Hwu>|Tg(Cdh5-cre)7Mlia|Ctnnb1<tm2Kem>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * BALB/c * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011092

文献

http://purl.org/net/cito/citesAsAuthority

• Wei. Guo, et.al., Multi-genetic events collaboratively contribute to Pten-null leukaemia stem-cell formation., Nature, 2008, 453
  http://rdf.ncbi.nlm.nih.gov/pubmed/18463637