embryonic lethality, complete penetrance_Npm1<tm1Gsva>/Npm1<tm1Gsva>,Dppa3<tm1(cre)Peli>/Dppa3<+>

http://metadb.riken.jp/0011092I129S5SvEvBrd129S7SvEvBrdNpm1tm1GsvaNpm1tm1GsvaDppa3tm1crePeliDppa3Dppa3tm1crePeliNpm1tm1GsvaDppa3

embryonic lethality, complete penetrance_Npm1<tm1Gsva>/Npm1<tm1Gsva>,Dppa3<tm1(cre)Peli>/Dppa3<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• developmental pluripotency-associated 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1920958
• nucleophosmin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:106184

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Npm1<tm1Gsva>/Npm1<tm1Gsva>,Dppa3<tm1(cre)Peli>/Dppa3<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Dppa3<tm1(cre)Peli>|Npm1<tm1Gsva>|Dppa3<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S5/SvEvBrd * 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality
  http://purl.obolibrary.org/obo/MP_0011092

文献

http://purl.org/net/cito/citesAsAuthority

• George S. Vassiliou, et.al., Mutant nucleophosmin and cooperating pathways drive leukemia initiation and progression in mice., Nature genetics, 2011, 43
  http://rdf.ncbi.nlm.nih.gov/pubmed/21441929