embryonic lethality before implantation, complete penetrance_Chek1<tm1Sje>/Chek1<tm1Sje>,Trp53<tm1Brd>/Trp53<tm1Brd>

http://metadb.riken.jp/0011094I129S7SvEvBrdChek1tm1SjeChek1tm1SjeTrp53tm1BrdTrp53tm1BrdTrp53tm1BrdChek1tm1Sje

embryonic lethality before implantation, complete penetrance_Chek1<tm1Sje>/Chek1<tm1Sje>,Trp53<tm1Brd>/Trp53<tm1Brd>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• checkpoint kinase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1202065
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Chek1<tm1Sje>/Chek1<tm1Sje>,Trp53<tm1Brd>/Trp53<tm1Brd>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brd>|Chek1<tm1Sje>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality before implantation
  http://purl.obolibrary.org/obo/MP_0011094

文献

http://purl.org/net/cito/citesAsAuthority

• Q. Liu, et.al., Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint., Genes & development, 2000, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/10859164