Q. Liu, et.al., Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint., Genes & development, 2000, 14

http://rdf.ncbi.nlm.nih.gov/pubmed/10859164

Q. Liu, et.al., Chk1 is an essential kinase that is regulated by Atr and required for the G(2)/M DNA damage checkpoint., Genes & development, 2000, 14

pubmed

allele

http://purl.org/net/cito/citesAsAuthority

• Chek1<tm1Sje>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926528
• Chek1<tm2.1Sje>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4818574

class

http://purl.org/net/cito/citesAsAuthority

• Chek1<tm1Sje>
  http://metadb.riken.jp/db/mgi_rdf/MGI:1926528
• Chek1<tm2.1Sje>
  http://metadb.riken.jp/db/mgi_rdf/MGI:4818574

表現型アノテーション

http://purl.org/net/cito/citesAsAuthority

• embryonic lethality before implantation, complete penetrance_Chek1<tm1Sje>/Chek1<tm1Sje>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0011094I129S7SvEvBrdChek1tm1SjeChek1tm1SjeTrp53tm1BrdTrp53tm1BrdTrp53tm1BrdChek1tm1Sje
• embryonic lethality before implantation, complete penetrance_Chek1<tm1Sje>/Chek1<tm1Sje>
  http://metadb.riken.jp/0011094NSChek1tm1SjeChek1tm1SjeChek1tm1Sje
• increased mammary adenocarcinoma incidence_Chek1<tm1Sje>/Chek1<+>,Tg(Wnt1)1Hev/0
  http://metadb.riken.jp/0001883NSChek1tm1SjeChek1TgWnt11Hev0Chek1TgWnt11HevChek1tm1Sje
• decreased cell proliferation_Chek1<tm1Sje>/Chek1<tm1Sje>
  http://metadb.riken.jp/0000352NSChek1tm1SjeChek1tm1SjeChek1tm1Sje
• increased embryonic tissue cell apoptosis_Chek1<tm1Sje>/Chek1<tm1Sje>
  http://metadb.riken.jp/0013504NSChek1tm1SjeChek1tm1SjeChek1tm1Sje
• abnormal cell cycle checkpoint function_Chek1<tm1Sje>/Chek1<tm1Sje>
  http://metadb.riken.jp/0004045NSChek1tm1SjeChek1tm1SjeChek1tm1Sje
• increased apoptosis_Chek1<tm1Sje>/Chek1<tm1Sje>,Trp53<tm1Brd>/Trp53<tm1Brd>
  http://metadb.riken.jp/0006042I129S7SvEvBrdChek1tm1SjeChek1tm1SjeTrp53tm1BrdTrp53tm1BrdTrp53tm1BrdChek1tm1Sje
• failure of blastocyst to hatch from the zona pellucida_Chek1<tm1Sje>/Chek1<tm1Sje>
  http://metadb.riken.jp/0003694NSChek1tm1SjeChek1tm1SjeChek1tm1Sje

トランスクリプトームデータ

http://rdf.ncbi.nlm.nih.gov/pubmed/

• CD12403
  http://metadb.riken.jp/db/BrainTx/TranscriptomeData/CD12403