embryonic lethality between implantation and placentation, complete penetrance_Gpx4<tm4Marc>/Gpx4<tm4Marc>

http://metadb.riken.jp/0011095I129S6SvEvTacC57BL6JGpx4tm4MarcGpx4tm4MarcGpx4tm4Marc

embryonic lethality between implantation and placentation, complete penetrance_Gpx4<tm4Marc>/Gpx4<tm4Marc>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• glutathione peroxidase 4
  http://metadb.riken.jp/db/mgi_rdf/MGI:104767

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gpx4<tm4Marc>/Gpx4<tm4Marc>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gpx4<tm4Marc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• complete embryonic lethality between implantation and placentation
  http://purl.obolibrary.org/obo/MP_0011095

文献

http://purl.org/net/cito/citesAsAuthority

• Irina. Ingold, et.al., Expression of a Catalytically Inactive Mutant Form of Glutathione Peroxidase 4 (Gpx4) Confers a Dominant-negative Effect in Male Fertility., The Journal of biological chemistry, 2015, 290
  http://rdf.ncbi.nlm.nih.gov/pubmed/25922076